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Description:
Excisase A (NifD element site-specific recombinase).
Molecular weight: 55228
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
base-excision repair( GO:0006284 )
Important dates:
01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
23-JAN-2002, sequence version 3.
07-MAR-2006, entry version 38.
Phylogenetic order:
Bacteria Cyanobacteria Nostocales Nostocaceae Nostoc.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein XISA_ANASP:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U38537 | AAC82961.1 | - |
| EMBL | BA000019 | BAB73399.1 | - |
| PIR | A24782 | A24782. | |
| PIR | AG1986 | AG1986. | |
| GenomeReviews | BA000019_GR | alr1442.1 | |
| BioCyc | NOST-PCC-01:NOST-PCC-01-001440-MONOMER | -.1 | |
| BioCyc | NSP103690:ALR1442-MONOMER | -.1 | |
| InterPro | IPR002104 | Phage_integrase. | |
| Pfam | PF00589 | Phage_integrase | 1. |
Keywords:
Complete proteome; DNA excision; DNA recombination; Heterocyst.
References:
RN [1]
RP PRELIMINARY NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX MEDLINE=86161679; PubMed=3006922; DOI=10.1016/0092-8674(86)90013-9;
RA Lammers P.J., Golden J.W., Haselkorn R.;
RT "Identification and sequence of a gene required for a developmentally
RT regulated DNA excision in Anabaena.";
RL Cell 44:905-911(1986).
RN [2]
RP SEQUENCE REVISION.
RA Carrasco C.D., Golden J.W.;
RL Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=21595285; PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S.,
RA Watanabe A., Iriguchi M., Ishikawa A., Kawashima K., Kimura T.,
RA Kishida Y., Kohara M., Matsumoto M., Matsuno A., Muraki A.,
RA Nakazaki N., Shimpo S., Sugimoto M., Takazawa M., Yamada M.,
RA Yasuda M., Tabata S.;
RT "Complete genomic sequence of the filamentous nitrogen-fixing
RT cyanobacterium Anabaena sp. strain PCC 7120.";
RL DNA Res. 8:205-213(2001).
RN [4]
RP FUNCTION.
RX MEDLINE=89072711; PubMed=3144039;
RA Golden J.W., Wiest D.R.;
RT "Genome rearrangement and nitrogen fixation in Anabaena blocked by
RT inactivation of xisA gene.";
RL Science 242:1421-1423(1988).
Feature:
CHAIN 1 472 Excisase A.
/FTId=PRO_0000066009.
CONFLICT 55 55 L -> S (in Ref. 1).
CONFLICT 82 82 G -> R (in Ref. 1).
CONFLICT 166 167 SE -> NK (in Ref. 1).
Comments:
-!- FUNCTION: Essential for DNA excision. Site specific recombinase
necessary for the excision of the 11 kb nifD element during
heterocyst differentiation.
-!- SIMILARITY: Belongs to the xisA/xisC recombinase family.
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Sequence length: 472
MQNQGQDKYQ QAFADLEPLS STDGSFLGSS LQAQQQREHM RTKVLQDLDK VNLRLKSAKT
KVSVRESNGS LQLRATLPIK PGDKDTNGTG RKQYNLSLNI PANLDGLKTA EEEAYELGKL
IARKTFEWND KYLGKEATKK DSQTIGDLLE KFAEEYFKTH KRTTKSEHTF FYYFSRTQRY
TNSKDLATAE NLINSIEQID KEWARYNAAR AISAFCITFN IEIDLSQYSK MPDRNSRNIP
TDAEILSGIT KFEDYLVTRG NQVNEDVKDS WQLWRWTYGM LAVFGLRPRE IFINPNIDWW
LSKENIDLTW KVDKECKTGE RQALPLHKEW IDEFDLRNPK YLEMLATAIS KKDKTNHAEI
TALTQRISWW FRKVELDFKP YDLRHAWAIR AHILGIPIKA AADNLGHSMQ VHTQTYQRWF
SLDMRKLAIN QALTKRNEFE VIREENAKLQ IENERLRMEI EKLKMEIAYK NS