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Description:
DNA mismatch repair protein mutS.
Molecular weight: 97797
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
01-OCT-2002, sequence version 1.
07-MAR-2006, entry version 19.
Phylogenetic order:
Bacteria Chlorobi Chlorobia Chlorobiales Chlorobiaceae Chlorobaculum.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein MUTS_CHLTE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE006470 | AAM72730.1 | - |
| HSSP | P23909 | 1NG9 | |
| GenomeReviews | AE006470_GR | CT1503.1 | |
| TIGR | CT1503 | -. | |
| BioCyc | CTEP194439:CT1503-MONOMER | -.1 | |
| HAMAP | MF_00096 | - | 1. |
| InterPro | IPR005748 | MutS1. | |
| InterPro | IPR000432 | MutS_C. | |
| InterPro | IPR007860 | MutS_II. | |
| InterPro | IPR007696 | MutS_III. | |
| InterPro | IPR007861 | MutS_IV. | |
| InterPro | IPR007695 | MutS_N. | |
| PANTHER | PTHR11361:SF23 | MutS.1 | 1. |
| Pfam | PF01624 | MutS_I | 1. |
| Pfam | PF05188 | MutS_II | 1. |
| Pfam | PF05192 | MutS_III | 1. |
| Pfam | PF05190 | MutS_IV | 1. |
| Pfam | PF00488 | MutS_V | 1. |
| ProDom | PD001263 | MutS_C | 1. |
| SMART | SM00534 | MUTSac | 1. |
| SMART | SM00533 | MUTSd | 1. |
| TIGRFAMs | TIGR01070 | mutS1 | 1. |
| PROSITE | PS00486 | DNA_MISMATCH_REPAIR_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLS / ATCC 49652 / DSM 12025;
RX MEDLINE=22103685; PubMed=12093901; DOI=10.1073/pnas.132181499;
RA Eisen J.A., Nelson K.E., Paulsen I.T., Heidelberg J.F., Wu M.,
RA Dodson R.J., DeBoy R.T., Gwinn M.L., Nelson W.C., Haft D.H.,
RA Hickey E.K., Peterson J.D., Durkin A.S., Kolonay J.F., Yang F.,
RA Holt I.E., Umayam L.A., Mason T.M., Brenner M., Shea T.P.,
RA Parksey D.S., Nierman W.C., Feldblyum T.V., Hansen C.L., Craven M.B.,
RA Radune D., Vamathevan J.J., Khouri H.M., White O., Gruber T.M.,
RA Ketchum K.A., Venter J.C., Tettelin H., Bryant D.A., Fraser C.M.;
RT "The complete genome sequence of Chlorobium tepidum TLS, a
RT photosynthetic, anaerobic, green-sulfur bacterium.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:9509-9514(2002).
Feature:
CHAIN 1 878 DNA mismatch repair protein mutS.
/FTId=PRO_0000115086.
NP_BIND 630 637 ATP (Potential).
Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
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Sequence length: 878
MAKSAQGRTK EPTPMMRQYL EVKERYPGYL LLFRVGDFYE TFLDDAVTVS SALNIVLTRR
SNGGAGEIPL AGFPHHASEG YIAKLVTKGF KVAVCDQVED PALAKGIVKR EITDIVTPGI
TYSDKILDDR HNNYLCAVAP VKRGREHMAG VAFVDVTTAE FRMTELPLGE LKDFLQSLRP
SEILISSRDK ELRESLAKSL FSGALFTTLD EWMFTEEQAA RVLENHFKTH SLKGFGIEGY
EAGRIAAGVI LQYLEEAKQG SLKYLVRIGL VESGETMTLD IQTCRNLEII SSMQDGSLNG
SLLEVIDRTK NPMGARLLRR WLLHPLRKLE PVVRRHDAVG ELLDAPEMRE GIRGMLGGII
DLERALARIA TSRAMPREVR QLGSSLAMIP QLKSLLEGSK SLRLRELALR LDPLPELAET
IEKALDAEAS GTLRDGGYIR AGYHAELDEL RAISSGARDR LLEIQQQERQ RTSISTLKVQ
YNKVFGYYIE VSRANSDKVP EYYEKKQTLV NAERYTIPAL KEYEEKILTA EEKSQLLEHQ
LFQELCAMIA EQAASIQTTA AALAELDCLA CFASCADEFG YCRPVMNEGT ELSIRAGRHP
VLERILGADE PYVANDCQVG SEQQLLIITG PNMAGKSSYL RQVGLVVLLA QVGCFVPAES
AEIGLVDRIF TRVGASDNLT SGESTFLVEM NEAASILNNA TERSLLLLDE IGRGTSTFDG
MSIAWSMCEY IHDQLRSRTL FATHYHELAE LESRFERIVN FNATVVETAD TVIFLRKIVR
GASDNSYGIE VAKMAGMPPE VIERAREILA GMERREVEVP VQRQALPLRV ESRQISLFEE
EESRLRKALS GIDINRLTPL DALMELKRLQ EIALGKGA