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Description:
Holliday junction ATP-dependent DNA helicase ruvB (EC 3.6.1.-).
Molecular weight: 40053
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
01-NOV-1997, sequence version 1.
07-MAR-2006, entry version 39.
Phylogenetic order:
Bacteria Cyanobacteria Chroococcales Synechocystis.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVB_SYNY3:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U38892 | AAA96396.1 | - |
| EMBL | BA000022 | BAA10350.1 | - |
| PIR | S76504 | S76504. | |
| HSSP | Q56313 | 1J7K | |
| GenomeReviews | BA000022_GR | sll0613.1 | |
| BioCyc | SSP1148:SLL0613-MONOMER | -.1 | |
| HAMAP | MF_00016 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR003959 | AAA_ATPase_centr. | |
| InterPro | IPR004605 | RuvB. | |
| InterPro | IPR008823 | RuvB_C. | |
| InterPro | IPR008824 | RuvB_N. | |
| InterPro | IPR011991 | Wing_hlx_DNA_bd. | |
| Pfam | PF00004 | AAA | 1. |
| Pfam | PF05491 | RuvB_C | 1. |
| Pfam | PF05496 | RuvB_N | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00635 | ruvB | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; Helicase; Hydrolase; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Bulteau S., Cassier-Chauvat C., Chauvat F.;
RT "Cloning, expression and inactivation of the ruvB gene from the
RT cyanobacterium Synechocystis PCC6803.";
RL Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=96127529; PubMed=8590279; DOI=10.1093/dnares/2.4.153;
RA Kaneko T., Tanaka A., Sato S., Kotani H., Sazuka T., Miyajima N.,
RA Sugiura M., Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. I. Sequence features in the 1 Mb
RT region from map positions 64% to 92% of the genome.";
RL DNA Res. 2:153-166(1995).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=97061201; PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T.,
RA Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S.,
RA Shimpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M.,
RA Tabata S.;
RT "Sequence analysis of the genome of the unicellular cyanobacterium
RT Synechocystis sp. strain PCC6803. II. Sequence determination of the
RT entire genome and assignment of potential protein-coding regions.";
RL DNA Res. 3:109-136(1996).
Feature:
CHAIN 1 361 Holliday junction ATP-dependent DNA
helicase ruvB.
/FTId=PRO_0000165616.
NP_BIND 81 88 ATP (Potential).
Comments:
-!- FUNCTION: The ruvA-ruvB complex in the presence of ATP renatures
cruciform structure in supercoiled DNA with palindromic sequence,
indicating that it may promote strand exchange reactions in
homologous recombination. RuvAB is an helicase that mediates the
Holliday junction migration by localized denaturation and
reannealing (By similarity).
-!- FUNCTION: Participates to UV-tolerance of Synechocystis PCC 6803.
-!- SUBUNIT: Forms a complex with ruvA.
-!- SIMILARITY: Belongs to the ruvB family.
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Sequence length: 361
MAIKRSGNNN LSPNVKSDLL SPEVIPQERS TSPELEQQEA SLRPQRLADY IGQRDLKEVL
RIAIQAAQGR QEAIDHLLLY GPPGLGKTTL ALILAEEMQV RCKITAAPAL ERPRDITGLL
LALQPGDILF IDEIHRLNRL TEELLYPAME DFRLDITMGK GQSAKVRSLK LAHFTLVGAT
TKVGSLTSPL RDRFGLIQRL RFYEVDELQQ IILRTAGILS VSISPTGAEA IAMRARGTPR
IANRLLKRVR DYAQVKQQPE IDPALASEAL DLYQVDKRGL DWTDRLVLQT LIEQFQGGPT
GLEAIAAATG EDAKTIEEVY EPYLLQIGYL ARTSRGRIAT TAAYEHLGLT PPTPLLPWKE
S