Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 15474
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-JUN-2002, sequence version 1.
07-MAR-2006, entry version 19.
Phylogenetic order:
Bacteria Firmicutes Clostridia Thermoanaerobacteriales Thermoanaerobacteriaceae Thermoanaerobacter.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_THETN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE013087 | AAM24474.1 | - |
| GenomeReviews | AE008691_GR | TTE1250.1 | |
| BioCyc | TTEN119072:TTE1250-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB4 / JCM 11007;
RX MEDLINE=21992816; PubMed=11997336; DOI=10.1101/gr.219302;
RA Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J.,
RA Chen Y., Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L.,
RA Tan H., Chen R., Wang J., Yu J., Yang H.;
RT "A complete sequence of the T. tengcongensis genome.";
RL Genome Res. 12:689-700(2002).
Feature:
CHAIN 1 139 Putative Holliday junction resolvase.
/FTId=PRO_0000172165.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 139
MRVLGLDVGD KTIGVAISDV SSTIAQGITT IRRKSFVEDV KAIEEIVKKY SVEKVVVGLP
KNMNGSIGPQ GEKVIKFGEK LREVLRIPVV FWDERLTTLQ AERFLIEGVD MSRGKRKKVI
DKLAATIILQ SYLDSQKNS