|
|
|
|
|
|
Description:
DNA replication and repair protein recF.
Molecular weight: 42415
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
21-DEC-2004, integrated into UniProtKB/Swiss-Prot.
21-DEC-2004, sequence version 1.
07-FEB-2006, entry version 8.
Phylogenetic order:
Bacteria Firmicutes Bacillales Staphylococcus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_STAAU:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | M86227 | AAA73950.1 | - |
| EMBL | X71437 | CAA50569.1 | - |
| PIR | S54710 | C40585. | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=YB886;
RX MEDLINE=95206242; PubMed=7898435; DOI=10.1007/BF00290713;
RA Alonso J.C., Fisher L.M.;
RT "Nucleotide sequence of the recF gene cluster from Staphylococcus
RT aureus and complementation analysis in Bacillus subtilis recF
RT mutants.";
RL Mol. Gen. Genet. 246:680-686(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 267-370.
RX MEDLINE=92165734; PubMed=1311298;
RA Margerrison E.E.C., Hopewell R., Fisher L.M.;
RT "Nucleotide sequence of the Staphylococcus aureus gyrB-gyrA locus
RT encoding the DNA gyrase A and B proteins.";
RL J. Bacteriol. 174:1596-1603(1992).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 282-370.
RC STRAIN=601055;
RX MEDLINE=93273692; PubMed=8388872;
RA Brockbank S.M.V., Barth P.T.;
RT "Cloning, sequencing, and expression of the DNA gyrase genes from
RT Staphylococcus aureus.";
RL J. Bacteriol. 175:3269-3277(1993).
Feature:
CHAIN 1 370 DNA replication and repair protein recF.
/FTId=PRO_0000196461.
NP_BIND 30 37 ATP (Potential).
CONFLICT 309 316 EYPILLLD -> NIPSYYC (in Ref. 2).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the recF family.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 370
MKLNTLQLEN YRNYDEVTLK CHPDVNILIG ENAQGKTNLL ESIYTLALAK SHRTSNDKEL
IRFNADYAKI EGELSYRHGT MPLTMFITKK GKQVKVNHLE QSRLTQYIGH LNVVLFAPED
LNIVKGSPQI RRRFIDMELG QISAVYLNDL AQYQRILKQK NNYLKQLQLG QKKDLTMLEV
LNQQFAEYAM KVTDKRAHFI QELESLAKPI HAGITNDKEA LSLNYLPSLK FDYAQNEAAR
LEEIMSILSD NMQREKERGI SLFGPHRDDI SFDVNGMDAQ TYGSQGQQRT TALSIKLAEI
ELMNIEVGEY PILLLDDVLS ELDDSRQTHL LSTIQHKVQT FVTTTSVDGI DHEIMNNAKL
YRINQGEIIK