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Description:
DNA replication and repair protein recF.
Molecular weight: 39141
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
07-MAR-2006, entry version 36.
Phylogenetic order:
Bacteria Deinococcus-Thermus Deinococci Deinococcales Deinococcaceae Deinococcus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_DEIRA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000513 | AAF10663.1 | - |
| PIR | A75438 | A75438. | |
| GenomeReviews | AE000513_GR | DR1089.1 | |
| TIGR | DR1089 | -. | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R1 / ATCC 13939 / DSM 20539 / NCIB 9279;
RX MEDLINE=20036896; PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA Fraser C.M.;
RT "Genome sequence of the radioresistant bacterium Deinococcus
RT radiodurans R1.";
RL Science 286:1571-1577(1999).
Feature:
CHAIN 1 359 DNA replication and repair protein recF.
/FTId=PRO_0000196413.
NP_BIND 33 40 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 359
MGDVRLSALS TLNYRNLAPG TLNFPEGVTG IYGENGAGKT NLLEAAYLAL TGQTDAPRIE
QLIQAGETEA YVRADLQQGG SLSIQEVGLG RGRRQLKVDG VRARTGDLPR GGAVWIRPED
SELVFGPPSG RRAYLDSLLS RLSARYGEQL SRYERTVSQR NAALRGGEEW AMHVWDDVLL
KLGTEIMLFR RRALTRLDEL AREANAQLGS RKTLALTLTE STSPETYAAD LRGRRAEELA
RGSTVTGPHR DDLLLTLGDF PASDYASRGE GRTVALALRR AELELLREKF GEDPVLLLDD
FTAELDPHRR QYLLDLAASV PQAIVTGTEL APGAALTLRA QAGRFTPVAD EEMQAEGTA