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Description:
Protein recA (Recombinase A).
Molecular weight: 41015
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
05-JUL-2004, integrated into UniProtKB/Swiss-Prot.
05-JUL-2004, sequence version 2.
07-MAR-2006, entry version 22.
Phylogenetic order:
Bacteria Firmicutes Lactobacillales Streptococcaceae Streptococcus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_STRAG:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AF326345 | AAK16709.1 | ALT_INIT |
| HSSP | P26345 | 1MO4 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 13813 / CIP 103227;
RA Chiou J.-F.;
RT "Cloning, sequencing and characterization of the RecA gene from
RT Streptococcus agalactiae.";
RL Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Feature:
CHAIN 1 379 Protein recA.
/FTId=PRO_0000122850.
NP_BIND 79 86 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage (By
similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 379
MAKKTKKAEE ITKKFGDERR KALDDALKNI EKDFGKGAVM RLGERAEQKV QVMSSGSLAL
DIALGAGGYP KGRIVEIYGP ESSGKTTVAL HAVAQAQKEG GIAAFIDAEH ALDPAYAAAL
GVNIDELLLS QPDSGEQDLE IAGKLIDSGA VDLVVVDSVA ALVPRAEIDG DIGDSHVGLQ
ARMMMQAMHK LTASINKTKT IAIFINQLRE KVGVMFGNPE TTPGGRALKF YSSVRLDVRG
NTQIKGTGEH KDHNVGKETK IKVVKNKVAP PFREAFVEIM YGEGISRTGE LIKIASDLDI
IQKAGAWYSY NGEKIGQGSE NAKKYLADNP AIFDEIDHKV RVHFGMTEDD SPVQSELVEE
KNEADDLVLD LDNAIEIEE