Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 16841
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 22.
Phylogenetic order:
Bacteria Firmicutes Mollicutes Mycoplasmataceae Ureaplasma.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_UREPA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE002134 | AAF30779.1 | - |
| GenomeReviews | AF222894_GR | UU370.1 | |
| BioCyc | UURE2130:UU370-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700970 / Serovar 3;
RX MEDLINE=20500219; PubMed=11048724; DOI=10.1038/35037619;
RA Glass J.I., Lefkowitz E.J., Glass J.S., Heiner C.R., Chen E.Y.,
RA Cassell G.H.;
RT "The complete sequence of the mucosal pathogen Ureaplasma
RT urealyticum.";
RL Nature 407:757-762(2000).
Feature:
CHAIN 1 147 Putative Holliday junction resolvase.
/FTId=PRO_0000172168.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 147
MRKLALDLGT KSCGFAISDL LGIIASGLDN FIYEENDFTA VLAKIDEIMI NYHHEIDTIV
LGYPTNVYDG SKNERTYLIE SFYALLKQHF LNHEKIKIVY EDERFSTKIA TQRLKNSCVK
AAKIKKVKDK MSAVVILESY LSKNHFN