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Description:
DNA replication and repair protein recF.
Molecular weight: 41356
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
04-MAY-2001, sequence version 1.
07-MAR-2006, entry version 30.
Phylogenetic order:
Bacteria Firmicutes Lactobacillales Streptococcaceae Lactococcus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_LACLA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE006427 | AAK06073.1 | - |
| PIR | G86871 | G86871. | |
| GenomeReviews | AE005176_GR | LL1975.1 | |
| BioCyc | LLAC1360:L0261-MONOMER | -.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL1403;
RX MEDLINE=21235186; PubMed=11337471; DOI=10.1101/gr.169701;
RA Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K.,
RA Weissenbach J., Ehrlich S.D., Sorokin A.;
RT "The complete genome sequence of the lactic acid bacterium Lactococcus
RT lactis ssp. lactis IL1403.";
RL Genome Res. 11:731-753(2001).
Feature:
CHAIN 1 358 DNA replication and repair protein recF.
/FTId=PRO_0000196422.
NP_BIND 30 37 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 358
MKLKAIELKN FRNYEELKLD FHPNLNIFLG QNAQGKTNIL EAIHFLALTR SHRTSHDKEL
ISWSQQEMKV SGVVEKAHAT VPLEVQLSPK GRIAKANHLK ENRLADYIGQ LKILMFAPEN
LELVKGSPAT RRKFMDIELG QIHAVYLYDS MRYNRALKER NAYLKFDKDK IDKNFLSVLD
GQLAEHGNKI MLERQNFIDK LEVHAKKIHE QLTHGKENLK IIYNQNVKTD FSKELLSRQD
HDIFRHQTSV GPHRDDLQFF INEINVADFG SQGQQRTVAL SIKLAEIDLI FEETGEYPIL
LLDDVMSELD NHRQLDLIET SLGKTQTFIT TTTLDHLKNL PENLSIFHVN AGTIEQEQ