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Description:
Protein recA (Recombinase A).
Molecular weight: 39949
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
01-NOV-1997, sequence version 1.
07-MAR-2006, entry version 38.
Phylogenetic order:
Bacteria Spirochaetes Spirochaetales Spirochaetaceae Borrelia Borrelia burgdorferi group.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_BORBU:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U23457 | AAA97557.1 | - |
| EMBL | AE001124 | AAC66507.1 | - |
| PIR | C70116 | C70116. | |
| HSSP | Q59560 | 1UBC | |
| GenomeReviews | AE000783_GR | BB0131.1 | |
| TIGR | BB0131 | -. | |
| BioCyc | BBUR139:BB0131-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Sh-2-82;
RX MEDLINE=96144263; PubMed=8566765; DOI=10.1016/0378-1119(95)00646-X;
RA Dew-Jager K., Yu W.Q., Huang W.M.;
RT "The recA gene of Borrelia burgdorferi.";
RL Gene 167:137-140(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35210 / B31;
RX MEDLINE=98065943; PubMed=9403685; DOI=10.1038/37551;
RA Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K.,
RA Gwinn M.L., Dougherty B.A., Tomb J.-F., Fleischmann R.D.,
RA Richardson D.L., Peterson J.D., Kerlavage A.R., Quackenbush J.,
RA Salzberg S.L., Hanson M., van Vugt R., Palmer N., Adams M.D.,
RA Gocayne J.D., Weidman J.F., Utterback T.R., Watthey L., McDonald L.A.,
RA Artiach P., Bowman C., Garland S.A., Fujii C., Cotton M.D., Horst K.,
RA Roberts K.M., Hatch B., Smith H.O., Venter J.C.;
RT "Genomic sequence of a Lyme disease spirochaete, Borrelia
RT burgdorferi.";
RL Nature 390:580-586(1997).
Feature:
CHAIN 1 365 Protein recA.
/FTId=PRO_0000122664.
NP_BIND 81 88 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 365
MSKLKEKREK AVVGIERASK EEAIELARVQ IEKAFGKGSL IKMGESPVGQ GIKSMSSGSI
VLDEALGIGG YPRGRIIEIF GPESSGKTTL TLQAIAEVQK EGGIAAFIDA EHALDPVYAK
ALGVNVAELW LSQPDTGEQA LEIAEHLIRS GGVDLIVVDS VAALTPKLEI DGEMGDSQIG
LQARLMSKAL RKITGILSKS NTCIMFINQI RMRIGVMFGN PETTTGGNAL KFYSSLRLEV
RKIEQVTRSG SSDDVIGNKI RVKIVKNKVA PPFRKVELII YFGKGISREA GILDAAIKHN
LIQKTGSWYS LGDNKLGQGR ESVIEYLSKE VELANNLDKR LRKIIFNNFD QENDNFIEFK
EDESE