Protein data for ADDB_BACSU:

Description:
ATP-dependent nuclease subunit B (EC 3.6.1.-) (ATP-dependent helicaseaddB).

Molecular weight: 1346

View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )

Important dates:
01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
01-NOV-1991, sequence version 1.
07-MAR-2006, entry version 44.

Phylogenetic order:
Bacteria Firmicutes Bacillales Bacillaceae Bacillus.

To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html

Links to references in other databases for protein ADDB_BACSU:

Database Pointer Add. info#1 Add. info#2
EMBL M63489 AAA22200.1 -
EMBL Y14081 CAA74481.1 -
EMBL Z99109 CAB12902.1 -
PIR A39432 A39432.
GenomeReviews AL009126_GR BSU10620.1
SubtiList BG10465 addB.
BioCyc BSUB1423:BSU1062-MONOMER -.1
InterPro IPR000212 UvrD-helicase.
Pfam PF00580 UvrD-helicase 1.

General information about the databases mentioned above

Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; Endonuclease; Exonuclease; Helicase; Hydrolase; Nuclease; Nucleotide-binding.

References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=OG1;
RX MEDLINE=91267926; PubMed=1646786;
RA Kooistra J., Venema G.;
RT "Cloning, sequencing, and expression of Bacillus subtilis genes
RT involved in ATP-dependent nuclease synthesis.";
RL J. Bacteriol. 173:3644-3655(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX MEDLINE=98240224; PubMed=9579061;
RA Noback M.A., Holsappel S., Kiewiet R., Terpstra P., Wambutt R.,
RA Wedler H., Venema G., Bron S.;
RT "The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the
RT Bacillus subtilis chromosome contains several dysfunctional genes, the
RT glyB marker, many genes encoding transporter proteins, and the
RT ubiquitous hit gene.";
RL Microbiology 144:859-875(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX MEDLINE=98044033; PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
RA Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
RA Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S.,
RA Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M.,
RA Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A.,
RA Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T.,
RA Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D.,
RA Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N.,
RA Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G.,
RA Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A.,
RA Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M.,
RA Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M.,
RA Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S.,
RA Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G.,
RA Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B.,
RA Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R.,
RA Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P.,
RA Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H.,
RA Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P.,
RA Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F.,
RA Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H.,
RA Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).

Feature:
CHAIN 1 1166 ATP-dependent nuclease subunit B.
/FTId=PRO_0000064450.
NP_BIND 8 15 ATP (Potential).

Comments:
-!- FUNCTION: The enzyme complex may have a wide variety of catalytic
activities including ATP-dependent exonuclease, ATP-stimulated
endonuclease, ATP-dependent helicase and DNA-dependent ATPase
activities.
-!- SUBUNIT: The B.subtilis ATP-dependent nuclease complex is formed
by one B subunit in conjunction with one A subunit.
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Sequence length: 1166

     MGAEFLVGRS GSGKTKLIIN SIQDELRRAP FGKPIIFLVP DQMTFLMEYE LAKTPDMGGM
     IRAQVFSFSR LAWRVLQHTG GMSRPFLTST GVQMLLRKLI EEHKQEFKVY QKASDKSGFT
     AQVERMLTEF KRYCLEPEDI RRMAESGTAS EYRGERVLSE KLHDLSILYQ QMEKSLADQY
     LHSEDYLTLL AEHIPLAEDI KGAHIYVDGF YQFTPQEFRV LEQLMVHAEH ITFSLTADKP
     SYEREPHELE LFRMTGKTYY RLHQKAKELN LDITYKELSG TERHTKTPEL AHLEAQYEAR
     PAIPYAEKQE ALTVMQAANR RAELEGIARE IHALVREKGY RYKDVAILAR QPEDYKDMVK
     EVFADYEIPY FIDGKASMLN HPLIEFIRSS LDVLKGNWRY EAVFRCVKTE LLFPLNEPKA
     KVREQVDQLE NYCIAYGIKG DRWTKGDRFQ YRRFVSLDDD FAQTDQEIEM ENMLNDTRDW
     IVPPLFQLQK RMKKAKTVQE KAEALYRYLE ETDVPLKLDQ ERQRAEDDGR IIEAQQHQQA
     WDAVIQLLEE FVEMMGDDEI SLDLFQQMIE AGAESLTFSL IPPALDQVFV GNMDLSRMYG
     TSCTFVLGAN DGVLPARPDE NGVLSDDDRE WLKTIGVELS SGGRERLLDE HFLIYMAFSS
     PSDRLYVSYP IADAEGKTLL PSMIVKRLEE LFPHHKERLL TNEPEQVSDE EQLMYVVNKS
     VAQSFTASQL RLWTREYDIS DVWWSTYNVL MSEQDRLQSK KLFSSLFFRN EVKQLERSVS
     RQLYGERIQG SVSRMETFNA CPFSHFASHG LHLKERQFFK LEAPDIGQLF HSSLKLISDR
     LRDEKLDWRD LTKEQCELFS YDAVERLAPK LQKEILLSSN RHYYVKEKLQ KIVTRVSGIL
     SEHAKASGFV PIGLELGFGG KGPLPPLTFQ LKNGCTMELV GRIDRVDKAE SSKGLLLRIV
     DYKSSDKGLD LAEVYYGLAL QMLTYLDLSI THSADWLGMR ATPAGVLYFH IHDPMIQSNL
     PLGLDEIEQE IFKKFKMKGL LLGDQEVVRL MDTTLQEGRS NIINAGLKKD GSLRSDSAAV
     GEKEFDLLTK HVRRTFQEAG EQITDGRVSI EPYKMKNKTP CTYCAFKSVC QFDESLEENE
     YRPLKAEKDK TILEWIKKEA DGNEHS

Back

Database	Pointer	Add. info#1	Add. info#2
EMBL	M63489	AAA22200.1	-
EMBL	Y14081	CAA74481.1	-
EMBL	Z99109	CAB12902.1	-
PIR	A39432	A39432.
GenomeReviews	AL009126_GR	BSU10620.1
SubtiList	BG10465	addB.
BioCyc	BSUB1423:BSU1062-MONOMER	-.1
InterPro	IPR000212	UvrD-helicase.
Pfam	PF00580	UvrD-helicase	1.