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Description:
DNA repair protein radA homolog (DNA repair protein sms homolog).
Molecular weight: 49483
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
01-OCT-1994, sequence version 1.
07-MAR-2006, entry version 50.
Phylogenetic order:
Bacteria Firmicutes Bacillales Bacillaceae Bacillus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_BACSU:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | D26185 | BAA05321.1 | - |
| EMBL | Z99104 | CAB11863.1 | - |
| EMBL | U02604 | AAA19234.1 | - |
| PIR | S66116 | S66116. | |
| GenomeReviews | AL009126_GR | BSU00870.1 | |
| SubtiList | BG10149 | radA. | |
| BioCyc | BSUB1423:BSU0087-MONOMER | -.1 | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001984 | Peptidase_S16. | |
| InterPro | IPR004504 | RadA. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00830 | ENDOLAPTASE. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX MEDLINE=96051385; PubMed=7584024; DOI=10.1093/dnares/1.1.1;
RA Ogasawara N., Nakai S., Yoshikawa H.;
RT "Systematic sequencing of the 180 kilobase region of the Bacillus
RT subtilis chromosome containing the replication origin.";
RL DNA Res. 1:1-14(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX MEDLINE=98044033; PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
RA Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
RA Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S.,
RA Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M.,
RA Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A.,
RA Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T.,
RA Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D.,
RA Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N.,
RA Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G.,
RA Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A.,
RA Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M.,
RA Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M.,
RA Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S.,
RA Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G.,
RA Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B.,
RA Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R.,
RA Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P.,
RA Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H.,
RA Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P.,
RA Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F.,
RA Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H.,
RA Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-259.
RC STRAIN=168 / Marburg;
RX MEDLINE=94286523; PubMed=8016066;
RA Msadek T., Kunst F., Rapoport G.;
RT "MecB of Bacillus subtilis, a member of the ClpC ATPase family, is a
RT pleiotropic regulator controlling competence gene expression and
RT growth at high temperature.";
RL Proc. Natl. Acad. Sci. U.S.A. 91:5788-5792(1994).
Feature:
CHAIN 1 458 DNA repair protein radA homolog.
/FTId=PRO_0000187921.
ZN_FING 10 27 C4-type (Potential).
NP_BIND 98 105 ATP (Potential).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage (By similarity).
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
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Sequence length: 458
MAKTKSKFIC QSCGYESPKW MGKCPGCGAW NTMVEEMIKK APANRRAAFS HSVQTVQKPS
PITSIETSEE PRVKTQLGEF NRVLGGGVVK GSLVLIGGDP GIGKSTLLLQ VSAQLSGSSN
SVLYISGEES VKQTKLRADR LGINNPSLHV LSETDMEYIS SAIQEMNPSF VVVDSIQTVY
QSDITSAPGS VSQVRECTAE LMKIAKTKGI PIFIVGHVTK EGSIAGPRLL EHMVDTVLYF
EGERHHTFRI LRAVKNRFGS TNEMGIFEMR EEGLTEVLNP SEIFLEERSA GSAGSSITAS
MEGTRPILVE IQALISPTSF GNPRRMATGI DHNRVSLLMA VLEKRVGLLL QNQDAYLKVA
GGVKLDEPAI DLAIVISIAS SFRDTPPNPA DCFIGEVGLT GEVRRVSRIE QRVKEAAKLG
FKRMIIPAAN LDGWTKPKGI EVIGVANVAE ALRTSLGG