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Description:
Protein recA (Recombinase A).
Molecular weight: 38090
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
01-AUG-1990, sequence version 1.
07-MAR-2006, entry version 58.
Phylogenetic order:
Bacteria Firmicutes Bacillales Bacillaceae Bacillus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_BACSU:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | X52132 | CAA36377.1 | - |
| EMBL | Z99112 | CAB13567.1 | - |
| EMBL | U87792 | AAB47709.1 | - |
| EMBL | U56238 | AAB00569.1 | - |
| PIR | S10370 | RQBSEE. | |
| HSSP | Q59560 | 1UBC | |
| GenomeReviews | AL009126_GR | BSU16940.1 | |
| SubtiList | BG10721 | recA. | |
| BioCyc | BSUB1423:BSU1695-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / YB886;
RX MEDLINE=90332424; PubMed=2115993;
RA Stranathan M.C., Bayles K.W., Yasbin R.E.;
RT "The nucleotide sequence of the recE+ gene of Bacillus subtilis.";
RL Nucleic Acids Res. 18:4249-4249(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX MEDLINE=98044033; PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G.,
RA Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S.,
RA Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S.,
RA Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M.,
RA Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A.,
RA Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T.,
RA Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D.,
RA Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N.,
RA Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G.,
RA Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A.,
RA Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M.,
RA Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M.,
RA Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S.,
RA Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G.,
RA Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B.,
RA Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R.,
RA Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P.,
RA Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H.,
RA Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P.,
RA Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F.,
RA Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H.,
RA Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-280.
RC STRAIN=PB1831;
RA de Rossi E.;
RT "Cloning of a putative mdr gene from Bacillus subtilis.";
RL Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-31.
RC STRAIN=168;
RA Albertini A., Caldwell B., Caramori T., Errington J., Foulger D.,
RA Thomaides H., Williams A.;
RT "The genetic organisation of the recA chromosomal region in Bacillus
RT subtilis.";
RL Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
Feature:
CHAIN 1 347 Protein recA.
/FTId=PRO_0000122656.
NP_BIND 64 71 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
Multifunctional protein involved in homologous recombination and
DNA repair.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- INDUCTION: By competence and damage.
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 347
MSDRQAALDM ALKQIEKQFG KGSIMKLGEK TDTRISTVPS GSLALDTALG IGGYPRGRII
EVYGPESSGK TTVALHAIAE VQQQRTSAFI DAEHALDPVY AQKLGVNIEE LLLSQPDTGE
QALEIAEALV RSGAVDIVVV DSVAALVPKA EIEGDMGDSH VGLQARLMSQ ALRKLSGAIN
KSKTIAIFIN QIREKVGVMF GNPETTPGGR ALKFYSSVRL EVRRAEQLKQ GNDVMGNKTK
IKVVKNKVAP PFRTAEVDIM YGEGISKEGE IIDLGTELDI VQKSGSWYSY EEERLGQGRE
NAKQFLKENK DIMLMIQEQI REHYGLDNNG VVQQQAEETQ EELEFEE