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Description:
DNA replication and repair protein recF.
Molecular weight: 42290
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
01-OCT-2001, sequence version 1.
07-MAR-2006, entry version 22.
Phylogenetic order:
Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_CLOAB:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE007513 | AAK77991.1 | - |
| PIR | D96900 | D96900. | |
| GenomeReviews | AE001437_GR | CAC0004.1 | |
| BioCyc | CACE1488:CAC0004-MONOMER | -.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 824 / DSM 792 / VKM B-1787;
RX MEDLINE=21359325; PubMed=11466286;
RX DOI=10.1128/JB.183.16.4823-4838.2001;
RA Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q.,
RA Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I.,
RA Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P.,
RA Daly M.J., Bennett G.N., Koonin E.V., Smith D.R.;
RT "Genome sequence and comparative analysis of the solvent-producing
RT bacterium Clostridium acetobutylicum.";
RL J. Bacteriol. 183:4823-4838(2001).
Feature:
CHAIN 1 363 DNA replication and repair protein recF.
/FTId=PRO_0000196406.
NP_BIND 30 37 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 363
MYIKNLYLDN FRNYDNIEID FNKKVNILTG NNAQGKTNIL ESIFYCSLGK SHRTNKDKEL
IKWDKDEAFI RLNLSRKPLD KKIEIKIFKG GKKGININSI KLKKISELFG IFNVVMFSPE
DLKIVKESPG HRRKFLDMEI SKLDHRYYYK LVQYNKILDQ RNIMLRNKKF LNNDMISVYD
EQLSKFGSSL IESRIKYLNK LNEKGKIIHS DITKGKEEIE FTYLTHVKGR ENISEELFSL
FKDSYKRDVE KGNTSVGPHR DDFSIKINGI DARSFGSQGQ QRTSVLTIKF ASIQIIKEIS
SETPVLLLDD VLSELDESRQ EYILNSLEGI QTLITCTGIG DIEKYLKNDF NVFRIDNGRI
AEY