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Description:
Protein recA (Recombinase A).
Molecular weight: 37955
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
07-MAR-2006, entry version 42.
Phylogenetic order:
Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_CLOPE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U61497 | AAC45139.1 | - |
| EMBL | BA000016 | BAB81379.1 | - |
| HSSP | P26345 | 1MO3 | |
| GenomeReviews | BA000016_GR | CPE1673.1 | |
| BioCyc | CPER1502:CPE1673-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=13 / Type A;
RX MEDLINE=97237717; PubMed=9084172;
RA Johnston J.L., Sloan J., Fyfe J.A.M., Davies J.K., Rood J.I.;
RT "The recA gene from Clostridium perfringens is induced by methyl
RT methanesulphonate and contains an upstream Cheo box.";
RL Microbiology 143:885-890(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13 / Type A;
RX MEDLINE=21664373; PubMed=11792842; DOI=10.1073/pnas.022493799;
RA Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A.,
RA Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT "Complete genome sequence of Clostridium perfringens, an anaerobic
RT flesh-eater.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
Feature:
CHAIN 1 352 Protein recA.
/FTId=PRO_0000122692.
NP_BIND 68 75 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 352
MANIDKDKLK AIEMAMGQIE KQFGKGSVMK LGEQGAPQMD AVSTGCLDLD IALGIGGVPK
GRIIEIYGPE SSGKTTVALH VVAEAQKLGG AAAYIDAEHA LDPVYAKRLG VNIDDLVVSQ
PDTGEQALEI TEALVRSGAI DVLVVDSVAA LVPRAEIEGE MGDSHVGLQA RLMSQALRKL
TGTINKSNCV VIFINQLREK VGIMFGNPET TPGGRALKFY ASVRMDIRRI DSIKQGDGIT
GNRTRVKIVK NKVAPPFKQA EFDIMYNEGI SKEGNIVDVG VKENIVQKSG AWFSYGDIRL
GQGRENAKQY LKENPAVALD IENQIREKYS LPLAKAVEST SVEENTEESV ES