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Description:
DNA replication and repair protein recF.
Molecular weight: 42215
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
01-MAR-2002, sequence version 1.
07-MAR-2006, entry version 21.
Phylogenetic order:
Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_CLOPE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000016 | BAB79710.1 | - |
| GenomeReviews | BA000016_GR | CPE0004.1 | |
| BioCyc | CPER1502:CPE0004-MONOMER | -.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13 / Type A;
RX MEDLINE=21664373; PubMed=11792842; DOI=10.1073/pnas.022493799;
RA Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A.,
RA Shiba T., Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT "Complete genome sequence of Clostridium perfringens, an anaerobic
RT flesh-eater.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
Feature:
CHAIN 1 361 DNA replication and repair protein recF.
/FTId=PRO_0000196407.
NP_BIND 30 37 ATP (Potential).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 361
MYIKSLQLIN YRNYENLSIK LCPNVNVFIG DNAQGKTNVI EAIYYCGFAK SHRTNRDKEL
IEWNKDRAFI RLDVHKDRLD KIIDVNILKD GKKAISINSI KISKIGELIG TFNVVMFSPE
DLKIVKESPG IRRRFIDMEL SQLNKRYYHN LVQYNKVLHE RNLVLKNKNI NEEMLDIYDI
QLAQYGENII KTRLKYIEQL NKYSKEIHKE ITSGKEEIEF KYISTVKDLD NIKDSMIKLL
EQNRKKDIDK RATSIGPHRD DFNIYLNNID AKIYGSQGQQ RTSVLTIKFA SLKIIKEITG
EYPVLLLDDV LSELDFNRKR YVLTSIKNIQ TVITCTGIED LTSYLDENSK VFRVINGRIQ
C