Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 15522
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
16-JUN-2003, sequence version 1.
07-MAR-2006, entry version 18.
Phylogenetic order:
Bacteria Firmicutes Clostridia Clostridiales Clostridiaceae Clostridium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_CLOTE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE015927 | AAO35639.1 | - |
| GenomeReviews | AE015927_GR | CTC01056.1 | |
| BioCyc | CTET212717:CTC01056-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Massachusetts / E88;
RX MEDLINE=22457253; PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H.,
RA Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A.,
RA Gottschalk G.;
RT "The genome sequence of Clostridium tetani, the causative agent of
RT tetanus disease.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
Feature:
CHAIN 1 138 Putative Holliday junction resolvase.
/FTId=PRO_0000172051.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 138
MRILGLDVGD RTIGVAISDP LGWTAQGVKT IKRSNLKNDI KEIEDICNEY KVDKIVSGLP
KNMNGTLGPQ SEKVTEFCDI LKKELEKEII MWDERLTTVA AHKAMIEGDL SRAKRKKIVD
KIAAIYILQG YLDSVYNK