|
|
|
|
|
|
Description:
Protein recA (Recombinase A).
Molecular weight: 41403
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
23-APR-2003, integrated into UniProtKB/Swiss-Prot.
01-MAR-2003, sequence version 1.
07-MAR-2006, entry version 25.
Phylogenetic order:
Bacteria Actinobacteria Actinobacteridae Actinomycetales Corynebacterineae Corynebacteriaceae Corynebacterium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_COREF:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000035 | BAC18659.1 | - |
| HSSP | P26345 | 1MO3 | |
| SMR | Q8FPD3 | 15-338.1 | |
| GenomeReviews | BA000035_GR | CE1849.1 | |
| BioCyc | CEFF196164:CE1849-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR002110 | ANK. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR01415 | ANKYRIN. | |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YS-314 / AJ 12310 / DSM 44549 / JCM 11189;
RX MEDLINE=22723752; PubMed=12840036; DOI=10.1101/gr.1285603;
RA Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E.,
RA Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K.,
RA Gojobori T.;
RT "Comparative complete genome sequence analysis of the amino acid
RT replacements responsible for the thermostability of Corynebacterium
RT efficiens.";
RL Genome Res. 13:1572-1579(2003).
Feature:
CHAIN 1 386 Protein recA.
/FTId=PRO_0000122695.
NP_BIND 76 83 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage (By
similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 386
MATKKTTKAA PKGDDRQKAL DAALALIEKD FGKGAVMRLG DENRPPIQVI SSGNTALDIA
LGIGGFPRGR IVEVYGPESS GKTTVALHAI AQAQKAGGIA AFIDAEHALD PDYARKLGVD
TDALLVSQPD TGEQALEIAD MLVRSGAIDI LVIDSVAALT PKAEIEGEMG DSHVGLQARL
MSQALRKMTG ALYNSGTTAI FINQLREKIG VMFGSPETTT GGKALKFYAS VRIDVRRIQT
LKDGQDAIGN RTRAKIVKNK VSPPFKIAEF DIIYGEGISR ESSIIDLAVD NGIVKKSGSW
FTYEGDQLGQ GKEKARLFLK ETPELADEIE EKIFRKLGVG KFAQTADELT DDPVELIPNV
DFDDEDDDFD ASTAPAGTFT EVTTEN