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Description:
Single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein).
Molecular weight: 23513
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
24-OCT-2003, sequence version 2.
07-MAR-2006, entry version 23.
Phylogenetic order:
Bacteria Actinobacteria Actinobacteridae Actinomycetales Corynebacterineae Corynebacteriaceae Corynebacterium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB_COREF:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000035 | BAC19629.1 | ALT_INIT |
| HSSP | P02339 | 1QVC | |
| SMR | Q8FLP9 | 4-120.1 | |
| GenomeReviews | BA000035_GR | CE2819.1 | |
| BioCyc | CEFF196164:CE2819-MONOMER | -.1 | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR011344 | Single_strand_bd. | |
| InterPro | IPR000424 | SSB_primosomal_n. | |
| InterPro | IPR010913 | ssDNA_bd. | |
| Pfam | PF00436 | SSB | 1. |
| TIGRFAMs | TIGR00621 | ssb | 1. |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YS-314 / AJ 12310 / DSM 44549 / JCM 11189;
RX MEDLINE=22723752; PubMed=12840036; DOI=10.1101/gr.1285603;
RA Nishio Y., Nakamura Y., Kawarabayasi Y., Usuda Y., Kimura E.,
RA Sugimoto S., Matsui K., Yamagishi A., Kikuchi H., Ikeo K.,
RA Gojobori T.;
RT "Comparative complete genome sequence analysis of the amino acid
RT replacements responsible for the thermostability of Corynebacterium
RT efficiens.";
RL Genome Res. 13:1572-1579(2003).
Feature:
CHAIN 1 232 Single-stranded DNA-binding protein.
/FTId=PRO_0000096033.
DOMAIN 1 111 SSB.
COMPBIAS 195 201 Poly-Gly.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosome. It is also involved in DNA recombination and repair
(By similarity).
-!- SIMILARITY: Contains 1 SSB domain.
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Sequence length: 232
MAQGDTNITV VGNLVADPEL RFTPSGAAVA NFRIASTPRT FNRTTNQWED GEGLFLTCNV
WREAAENVAE SLTKGMRVIV QGRLRQRSYE TREGEKRTIF EVEVDDVGPS LKYAKAEVTR
IPRGGGQGGF GGNQGGGFGG QGGNQGGNPG GGQGGFGQNT GGFGGQQGNQ GGFGGGQGGN
PGGNQGQSGN NFNQGGFGGG GNQAAAPDND PWNSAPPAGS GGFGGADDEP PF