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Description:
DNA mismatch repair protein mutS.
Molecular weight: 95112
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
01-JUN-2003, sequence version 1.
07-MAR-2006, entry version 20.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein MUTS_PSEPK:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE015451 | AAN67247.1 | - |
| HSSP | P23909 | 1NG9 | |
| GenomeReviews | AE015451_GR | PP1626.1 | |
| TIGR | PP1626 | -. | |
| HAMAP | MF_00096 | - | 1. |
| InterPro | IPR005748 | MutS1. | |
| InterPro | IPR000432 | MutS_C. | |
| InterPro | IPR007860 | MutS_II. | |
| InterPro | IPR007696 | MutS_III. | |
| InterPro | IPR007861 | MutS_IV. | |
| InterPro | IPR007695 | MutS_N. | |
| PANTHER | PTHR11361:SF23 | MutS.1 | 1. |
| Pfam | PF01624 | MutS_I | 1. |
| Pfam | PF05188 | MutS_II | 1. |
| Pfam | PF05192 | MutS_III | 1. |
| Pfam | PF05190 | MutS_IV | 1. |
| Pfam | PF00488 | MutS_V | 1. |
| ProDom | PD001263 | MutS_C | 1. |
| SMART | SM00534 | MUTSac | 1. |
| SMART | SM00533 | MUTSd | 1. |
| TIGRFAMs | TIGR01070 | mutS1 | 1. |
| PROSITE | PS00486 | DNA_MISMATCH_REPAIR_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=22423060; PubMed=12534463;
RX DOI=10.1046/j.1462-2920.2002.00366.x;
RA Nelson K.E., Weinel C., Paulsen I.T., Dodson R.J., Hilbert H.,
RA Martins dos Santos V.A.P., Fouts D.E., Gill S.R., Pop M., Holmes M.,
RA Brinkac L.M., Beanan M.J., DeBoy R.T., Daugherty S.C., Kolonay J.F.,
RA Madupu R., Nelson W.C., White O., Peterson J.D., Khouri H.M.,
RA Hance I., Chris Lee P., Holtzapple E.K., Scanlan D., Tran K.,
RA Moazzez A., Utterback T.R., Rizzo M., Lee K., Kosack D., Moestl D.,
RA Wedler H., Lauber J., Stjepandic D., Hoheisel J., Straetz M., Heim S.,
RA Kiewitz C., Eisen J.A., Timmis K.N., Duesterhoeft A., Tuemmler B.,
RA Fraser C.M.;
RT "Complete genome sequence and comparative analysis of the
RT metabolically versatile Pseudomonas putida KT2440.";
RL Environ. Microbiol. 4:799-808(2002).
Feature:
CHAIN 1 857 DNA mismatch repair protein mutS.
/FTId=PRO_0000115122.
NP_BIND 613 620 ATP (Potential).
Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
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Sequence length: 857
MSDLSAHTPM MQQYWKLKNQ HPDQLMFYRM GDFYEIFYED AKKAAKLLDI TLTARGQSAG
QSIPMCGIPF HSLEGYLAKL VKLGESVVIC EQIGDPATSK GPVERQVVRI ITPGTVSDEA
LLDERRDNLI AALLGDERLF GLAVLDITSG NFSVQEIKGW ENLLAELERL NPVELLIPDD
WPRDLPAEKR PGARRRAPWD FDRDSARKAL CQQFATKDLK GFGCDKLTLA IGAAGCLLTY
AKETQRTALP HLRSLRHERL DDTVILDGAS RRNLELDINL AGGRDNTLQS VIDRCQTAMA
SRLLSRWLNR PLRDLKVLQA RQDSIRCLLD SYRFEKLQPQ LKEIGDIERI LARIGLRNAR
PRDLARLRDA LGALPELQNA MTELEAPHLA RLAAITGTYP ELASLLERAI IDNPPAVIRD
GGVLKAGYDN ELDELLAISE NAGQFLIDLE AREKARTGLA NLKVGYNRVH GYFIELPTKQ
AEQAPGDYIR RQTLKGAERF ITPELKAFED KALSAKSRAL AREKMLYDAL LETLISHLAP
LQDSAAALAE LDVLSNLAER ALNLDLNCPR FVDEPCLRIE QGRHPVVEQV LTTPFVANDL
GLDNSTRMLI ITGPNMGGKS TYMRQTALIV LLAHIGSFVP AASCELSLVD RIFTRIGSSD
DLAGGRSTFM VEMSETANIL HNATDRSLVL MDEVGRGTST FDGLSLAWAA AERLAQLRAY
TLFATHYFEL TVLPESEPLV ANVHLNATEH NERIVFLHHV LPGPASQSYG LAVAQLAGVP
TAVIQRAREH LGRLETTSLP HEQPAAHKAK DAPQVPHQSD LFASLPHPAI EKLGKLQLDD
MTPRQAIEML YQLKNLL