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Description:
Protein recA (Recombinase A).
Molecular weight: 44216
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
01-NOV-1998, sequence version 1.
07-MAR-2006, entry version 38.
Phylogenetic order:
Bacteria Spirochaetes Spirochaetales Spirochaetaceae Treponema.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_TREPA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000520 | AAC65660.1 | - |
| PIR | A71293 | A71293. | |
| HSSP | P26345 | 1MO3 | |
| GenomeReviews | AE000520_GR | TP0692.1 | |
| TIGR | TP0692 | -. | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nichols;
RX MEDLINE=98332770; PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M.,
RA Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D.,
RA Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M.,
RA Weidman J.F., Smith H.O., Venter J.C.;
RT "Complete genome sequence of Treponema pallidum, the syphilis
RT spirochete.";
RL Science 281:375-388(1998).
Feature:
CHAIN 1 407 Protein recA.
/FTId=PRO_0000122886.
NP_BIND 79 86 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 407
MSKALKGDVP VSSSFEEKMK ALEAARLQIE KQFGQGSLMK LGKDDAVQGV EVIPTGNILL
DEALGIGGYP RGRIIEIFGP ESSGKTTLAL HAVAEAQKRG GIAAFIDAEH ALDPQYAKDL
GVSVGDLWIS QPDTGEQALE IAESLVRSGA VDIIVVDSVA ALTPQAEIQG DMGDAHVGLI
ARLMSQALRK LTSIINKSKC TLIFINQLRM KIGIMFGNPE TTTGGIALKF YSSVRIEVRK
VETLSRGDEE AWGNKVRIRI VKNKMAPPFR KVETEILFGK GFSAFSCLLD AAVKQEIIEK
KGAWYAYREE KIGQGRDNAV GFLQQNMDIT LEIERAVRTK LFPKQAFISS FQEHRPALSL
EASPEESDAK TLRRXASRGA GASSSRVQEG SAANDHFQDE STTAKLL