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Description:
Single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein).
Molecular weight: 19043
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-NOV-1998, sequence version 1.
07-MAR-2006, entry version 34.
Phylogenetic order:
Bacteria Spirochaetes Spirochaetales Spirochaetaceae Treponema.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB_TREPA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000520 | AAC65057.1 | - |
| PIR | F71370 | F71370. | |
| HSSP | P02339 | 1EYG | |
| GenomeReviews | AE000520_GR | TP0062.1 | |
| TIGR | TP0062 | -. | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR011344 | Single_strand_bd. | |
| InterPro | IPR000424 | SSB_primosomal_n. | |
| InterPro | IPR010913 | ssDNA_bd. | |
| Pfam | PF00436 | SSB | 1. |
| TIGRFAMs | TIGR00621 | ssb | 1. |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nichols;
RX MEDLINE=98332770; PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M.,
RA Utterback T.R., McDonald L.A., Artiach P., Bowman C., Cotton M.D.,
RA Fujii C., Garland S.A., Hatch B., Horst K., Roberts K.M., Sandusky M.,
RA Weidman J.F., Smith H.O., Venter J.C.;
RT "Complete genome sequence of Treponema pallidum, the syphilis
RT spirochete.";
RL Science 281:375-388(1998).
Feature:
CHAIN 1 176 Single-stranded DNA-binding protein.
/FTId=PRO_0000096130.
DOMAIN 4 106 SSB.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosome. It is also involved in DNA recombination and repair
(By similarity).
-!- SIMILARITY: Contains 1 SSB domain.
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Sequence length: 176
MADVNHVVLV GRLTRDAELK YTSAGGALCR FSVAINRRRK SGDDWVEEVN FFDIVLWGRQ
GEVISQYLIK GKQVAVEGEL RQSRWEQEGQ SRSKVEISAT NVQLLGSVLG GAARAEDGEF
SSSRVAAEST AGRVRGTSSD SRSPTGDILG EKRGLDATSS LDEADFSSSD LDTVPF