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Description:
DNA repair protein radA homolog (DNA repair protein sms homolog).
Molecular weight: 49982
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
05-DEC-2001, sequence version 2.
07-MAR-2006, entry version 40.
Phylogenetic order:
Bacteria Firmicutes Bacillales Listeriaceae Listeria.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_LISMO:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U40604 | AAC44447.1 | - |
| EMBL | AF083254 | AAC33293.1 | - |
| EMBL | AL591974 | CAD00760.1 | - |
| PIR | AB1104 | AB1104. | |
| GenomeReviews | AL591824_GR | lmo0233.1 | |
| ListiList | LMO00233 | -.1 | |
| BioCyc | LMON169963:LMO0233-MONOMER | -.1 | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LO28 / Serovar 1/2c;
RX MEDLINE=97039716; PubMed=8885268;
RA Rouquette C., Ripio M.T., Pellegrini E., Bolla J.M., Tascon R.I.,
RA Vazquez-Boland J.A., Berche P.;
RT "Identification of a ClpC ATPase required for stress tolerance and in
RT vivo survival of Listeria monocytogenes.";
RL Mol. Microbiol. 21:977-987(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=2175 / Serovar 4b;
RA Truong T.K., Kathariou S.;
RL Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EGD-e / Serovar 1/2a;
RX MEDLINE=21537279; PubMed=11679669; DOI=10.1126/science.1063447;
RA Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A.,
RA Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T.,
RA Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P.,
RA Domann E., Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O.,
RA Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P.,
RA Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D.,
RA Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G.,
RA Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H.,
RA Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R.,
RA Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A.,
RA Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT "Comparative genomics of Listeria species.";
RL Science 294:849-852(2001).
Feature:
CHAIN 1 457 DNA repair protein radA homolog.
/FTId=PRO_0000187931.
ZN_FING 12 29 C4-type (Potential).
NP_BIND 97 104 ATP (Potential).
CONFLICT 37 37 E -> K (in Ref. 2).
CONFLICT 73 73 E -> Q (in Ref. 2).
CONFLICT 75 75 N -> S (in Ref. 2).
CONFLICT 86 86 G -> S (in Ref. 2).
CONFLICT 132 132 Q -> R (in Ref. 2).
CONFLICT 181 181 S -> P (in Ref. 1 and 2).
CONFLICT 197 197 T -> S (in Ref. 2).
CONFLICT 226 227 PR -> AP (in Ref. 2).
CONFLICT 244 244 H -> P (in Ref. 2).
CONFLICT 256 256 R -> P (in Ref. 2).
CONFLICT 260 261 TN -> PI (in Ref. 2).
CONFLICT 290 290 G -> S (in Ref. 2).
CONFLICT 293 293 G -> R (in Ref. 2).
CONFLICT 299 317 SMEGTRPVLVEIQALVSPT -> LWKNSPRPCGNTSACFAN
(in Ref. 1).
CONFLICT 403 403 R -> C (in Ref. 2).
CONFLICT 404 404 R -> S (in Ref. 1).
CONFLICT 424 424 F -> S (in Ref. 1).
CONFLICT 452 455 Missing (in Ref. 1).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage (By similarity).
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
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Sequence length: 457
MAKAKRTTKF VCQACGYESA KWMGKCPNCN EWNQMVEALE PSKKSRSAFN HTGEPSKATP
ITQIASETEK RVETNMPELN RVLGGGVVPG SMVLVGGDPG IGKSTLLLQV SAQLTLTNKK
VLYISGEESI KQTKLRAERL QVSGDNLYVY AETNLEAVQE TIDFVKPDFV VIDSIQTVYH
SDVTSAAGSV SQVRECTATL MRIAKMQNIA IFIVGHVTKE GAIAGPRLLE HMVDTVLYFE
GERHHAYRIL RAVKNRFGST NEMGIFEMRD VGLVEVANPS EVFLEERLEG ASGSTVVASM
EGTRPVLVEI QALVSPTMFG NAKRMATGID YNKVSLIMAV LEKRVGLMLQ NQDAYLKAAG
GVKLDEPAVD LAVAVSVASS YRDKPTRSTD CFIGELGLTG EIRRVARIEQ RVQEAAKLGF
KRIFIPKNNE GNWKIPKDVQ VVGVETIGEA LKKALPD