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Description:
DNA mismatch repair protein mutS.
Molecular weight: 98215
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
01-DEC-2001, sequence version 1.
07-MAR-2006, entry version 22.
Phylogenetic order:
Bacteria Firmicutes Bacillales Listeriaceae Listeria.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein MUTS_LISIN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL596168 | CAC96671.1 | - |
| PIR | AG1612 | AG1612. | |
| HSSP | P23909 | 1NG9 | |
| GenomeReviews | AL592022_GR | lin1440.1 | |
| ListiList | LIN01440 | -.1 | |
| BioCyc | LINN1642:LIN1440-MONOMER | -.1 | |
| HAMAP | MF_00096 | - | 1. |
| InterPro | IPR005748 | MutS1. | |
| InterPro | IPR000432 | MutS_C. | |
| InterPro | IPR007860 | MutS_II. | |
| InterPro | IPR007696 | MutS_III. | |
| InterPro | IPR007861 | MutS_IV. | |
| InterPro | IPR007695 | MutS_N. | |
| PANTHER | PTHR11361:SF23 | MutS.1 | 1. |
| Pfam | PF01624 | MutS_I | 1. |
| Pfam | PF05188 | MutS_II | 1. |
| Pfam | PF05192 | MutS_III | 1. |
| Pfam | PF05190 | MutS_IV | 1. |
| Pfam | PF00488 | MutS_V | 1. |
| ProDom | PD001263 | MutS_C | 1. |
| SMART | SM00534 | MUTSac | 1. |
| SMART | SM00533 | MUTSd | 1. |
| TIGRFAMs | TIGR01070 | mutS1 | 1. |
| PROSITE | PS00486 | DNA_MISMATCH_REPAIR_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIP 11262 / Serovar 6a;
RX MEDLINE=21537279; PubMed=11679669; DOI=10.1126/science.1063447;
RA Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A.,
RA Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T.,
RA Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P.,
RA Domann E., Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O.,
RA Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P.,
RA Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D.,
RA Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G.,
RA Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H.,
RA Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R.,
RA Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A.,
RA Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT "Comparative genomics of Listeria species.";
RL Science 294:849-852(2001).
Feature:
CHAIN 1 860 DNA mismatch repair protein mutS.
/FTId=PRO_0000115108.
NP_BIND 607 614 ATP (Potential).
Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
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Sequence length: 860
MTEYTPMIKQ YLEIKDKYQD AFLFFRLGDF YEMFFEDALN ASQILEITLT GREGGTKEKI
PMCGVPYHSA SGYIDTLIEK GYKVAICEQV EDPKTTKGMV KREVVQLISP GTVMDERGLK
AKENNYIASL YCYEGKEYGF AYSDLSTGEL KSTVIEASED RLINELTTLS TRELIVSESE
KEVLSDVMKE QLGLTFSVHE EDTIPAENEK LVTRHMSLSE KRAIGKLLHY LKETQKRDLG
HLQQAIHYET SNYMKMDYYS KRNLELAESI RGKGRQGTLL WLLDNTQTAM GGRMLKQWID
RPLIDRKQII ERQDDVSELM AHFFERLELV ENLKNVYDLE RLAGRVAYGN VNARDLIQLR
NSLYQIPRIR ATLLSMNSKS LTALANQLDP CEELTEKLEE AIVDSAPISI REGGIIKDGY
NSQLDTYRDA SRNGKTWIAE LERKERELTG IKTMKVGFNR VFGYYIEVTR ANTHLLPEGR
YERKQTLANA ERYITPELKE KEKLILDAEE KSMELEYQLF TEVREMVKDY IERLQKLAKS
VSEIDCLQSF ADISEKNHFI RPTLSEDGSL HVKQGRHPVV EKVMGAQSYV ANDCDLDQNR
EILLITGPNM SGKSTYMRQV ALTAICAQVG CFVPAEEATL PIFDQIFTRI GAADDLIAGQ
STFMVEMLEA RNAIVHATKD SLILFDEIGR GTATYDGMAL AQAIIEYIHE NVHAKTLFST
HYHELTDLEK ELRGLQNIHV SAVEENGKVV FLHKIKEGPA DKSYGIHVAE LAELPKSLIE
RASRILEQLE SNDKKIIITQ DKQPEEIHEE VQLSMFPVEP EEKASSKETK LLKEIAAMNI
MQMTPMDAMN KLYELQSKIH