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Description:
Protein recA (Recombinase A).
Molecular weight: 38802
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
01-OCT-1993, sequence version 1.
07-MAR-2006, entry version 45.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rhizobiales Rhizobiaceae Agrobacterium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_AGRT5:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | L07902 | NOT_ANNOTATED_CDS | |
| EMBL | AE009141 | AAL42870.1 | - |
| EMBL | AE008107 | AAK87640.1 | ALT_INIT |
| PIR | AH2806 | AH2806. | |
| PIR | JC1377 | JC1377. | |
| HSSP | P03017 | 2REB | |
| GenomeReviews | AE007869_GR | AGR_C_3441.1 | |
| GenomeReviews | AE008688_GR | Atu1874.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX MEDLINE=93051348; PubMed=1427086; DOI=10.1016/0378-1119(92)90171-K;
RA Wardhan H., McPherson M.J., Harris C.A., Sharma E., Sastry G.R.K.;
RT "Molecular analysis of the recA gene of Agrobacterium tumefaciens
RT C58.";
RL Gene 121:133-136(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=21608550; PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P.,
RA Okura V.K., Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L.,
RA Chen Y., Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr.,
RA Chapman P., Clendenning J., Deatherage G., Gillet W., Grant C.,
RA Kutyavin T., Levy R., Li M.-J., McClelland E., Palmieri A.,
RA Raymond C., Rouse G., Saenphimmachak C., Wu Z., Romero P., Gordon D.,
RA Zhang S., Yoo H., Tao Y., Biddle P., Jung M., Krespan W., Perry M.,
RA Gordon-Kamm B., Liao L., Kim S., Hendrick C., Zhao Z.-Y., Dolan M.,
RA Chumley F., Tingey S.V., Tomb J.-F., Gordon M.P., Olson M.V.,
RA Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=21608551; PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M.,
RA Qurollo B., Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L.,
RA Houmiel K., Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F.,
RA Wollam C., Allinger M., Doughty D., Scott C., Lappas C., Markelz B.,
RA Flanagan C., Crowell C., Gurson J., Lomo C., Sear C., Strub G.,
RA Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
Feature:
CHAIN 1 363 Protein recA.
/FTId=PRO_0000122636.
NP_BIND 77 84 ATP (By similarity).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 363
MAQNSLRLVE DKSVDKSKAL EAALSQIERS FGKGSIMKLG SNENVVEVET VSTGSLSLDI
ALGIGGLPKG RIIEIYGPES SGKTTLALQT IAEAQKKGGI CAFVDAEHAL DPVYARKLGV
DLQSLLISQP DTGEQALEIT DTLVRSGAVD VLVIDSVAAL TPRAEIEGEM GDSLPGLQAR
LMSQALRKLT ASISKSKCMV IFINQIRMKI GVMFGSPETT TGGNALKFYA SVRLDIRRIG
AVKEREEVVG NQTRVKVVKN KMAPPFKQVE FDIMYGEGVS KTGELVDLGV KAGIVEKSGA
WFSYNSQRLG QGRENAKTFL RDNPDTANEI ELALRQNAGL IADRFLQNGG PDAGEGDDGS
DEG