Description:
Putative 3-methyladenine DNA glycosylase (EC 3.2.2.-).
Molecular weight: 21340
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) base-excision repair( GO:0006284 )
Important dates:
11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
11-OCT-2004, sequence version 1.
07-MAR-2006, entry version 11.
Phylogenetic order:
Bacteria Actinobacteria Actinobacteridae Actinomycetales Corynebacterineae Mycobacteriaceae Mycobacterium Mycobacterium tuberculosis complex.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein 3MGH_MYCTU:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BX842577 | CAB10945.1 | - |
| EMBL | AE000516 | AAK45996.1 | - |
| PIR | G70501 | G70501. | |
| HSSP | P29372 | 1F6O | |
| GenomeReviews | AE000516_GR | MT1727.1.1 | |
| GenomeReviews | AL123456_GR | Rv1688.1 | |
| TIGR | MT1727.1 | -. | |
| TubercuList | Rv1688 | -. | |
| HAMAP | MF_00527 | - | 1. |
| InterPro | IPR003180 | PurDNA_glycsylse. | |
| PANTHER | PTHR10429 | PurDNA_glycsylse.1 | 1. |
| Pfam | PF02245 | Pur_DNA_glyco | 1. |
| ProDom | PD009649 | PurDNA_glycsylse | 1. |
| TIGRFAMs | TIGR00567 | 3mg | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; Hydrolase; Hypothetical protein.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H37Rv;
RX MEDLINE=98295987; PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M.,
RA Harris D.E., Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III,
RA Tekaia F., Badcock K., Basham D., Brown D., Chillingworth T.,
RA Connor R., Davies R.M., Devlin K., Feltwell T., Gentles S., Hamlin N.,
RA Holroyd S., Hornsby T., Jagels K., Krogh A., McLean J., Moule S.,
RA Murphy L.D., Oliver S., Osborne J., Quail M.A., Rajandream M.A.,
RA Rogers J., Rutter S., Seeger K., Skelton S., Squares S., Squares R.,
RA Sulston J.E., Taylor K., Whitehead S., Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the
RT complete genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX MEDLINE=22206494; PubMed=12218036;
RX DOI=10.1128/JB.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H.,
RA Hickey E.K., Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D.,
RA Salzberg S.L., Delcher A., Utterback T.R., Weidman J.F., Khouri H.M.,
RA Gill J., Mikula A., Bishai W., Jacobs W.R. Jr., Venter J.C.,
RA Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
Feature:
CHAIN 1 203 Putative 3-methyladenine DNA glycosylase.
/FTId=PRO_0000100094.
Comments:
-!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 203
MNAEELAIDP VAAAHRLLGA TIAGRGVRAM VVEVEAYGGV PDGPWPDAAA HSYRGRNGRN
DVMFGPPGRL YTYRSHGIHV CANVACGPDG TAAAVLLRAA AIEDGAELAT SRRGQTVRAV
ALARGPGNLC AALGITMADN GIDLFDPSSP VRLRLNDTHR ARSGPRVGVS QAADRPWRLW
LTGRPEVSAY RRSSRAPARG ASD