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Description:
Protein recA (Recombinase A).
Molecular weight: 37049
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
01-DEC-2000, sequence version 2.
07-MAR-2006, entry version 37.
Phylogenetic order:
Bacteria Proteobacteria Epsilonproteobacteria Campylobacterales Campylobacteraceae Campylobacter.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_CAMJE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U03121 | AAA17793.1 | - |
| EMBL | AL139079 | CAB73660.1 | - |
| PIR | F81264 | F81264. | |
| PIR | I40770 | I40770. | |
| HSSP | P26345 | 1MO3 | |
| GenomeReviews | AL111168_GR | Cj1673c.1 | |
| BioCyc | CJEJ192222:CJ1673C-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 55026 / 81-176;
RX MEDLINE=94131574; PubMed=8300203;
RA Guerry P., Pope P.M., Burr D.H., Leifer J., Joseph S.W.,
RA Bourgeois A.L.;
RT "Development and characterization of recA mutants of Campylobacter
RT jejuni for inclusion in attenuated vaccines.";
RL Infect. Immun. 62:426-432(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 11168;
RX MEDLINE=20150912; PubMed=10688204; DOI=10.1038/35001088;
RA Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M.,
RA Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S.,
RA Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W.,
RA Quail M.A., Rajandream M.A., Rutherford K.M., van Vliet A.H.M.,
RA Whitehead S., Barrell B.G.;
RT "The genome sequence of the food-borne pathogen Campylobacter jejuni
RT reveals hypervariable sequences.";
RL Nature 403:665-668(2000).
Feature:
CHAIN 1 343 Protein recA.
/FTId=PRO_0000122677.
NP_BIND 65 72 ATP (By similarity).
CONFLICT 217 217 F -> I (in Ref. 1).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 343
MDDNKRKSLD AALKSLDKTF GKGTILRLGD KEVEQIDSIG TGSVGLDLAL GIGGVPKGRI
IEIYGPESSG KTTLTLHIIA ECQKAGGVCA FIDAEHALDV KYAKNLGVNT DDLYVSQPDF
GEQALEIVET IARSGAVDLI VVDSVAALTP KAEIEGDMGD QHVGLQARLM SQALRKLTGI
VHKMNTTVIF INQIRMKIGA MGYGTPETTT GGNALKFYAS VRLDVRKVAT LKQNEEPIGN
RVKVKVVKNK VAPPFRQAEF DVMFGEGLSR EGELIDYGVK LDIVDKSGAW FSYKDKKLGQ
GRENSKAFLK ENPEIADEIT KAIQNSMGIE GMISGSEDDE GEE