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Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 14089
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 28.
Phylogenetic order:
Bacteria Proteobacteria Epsilonproteobacteria Campylobacterales Campylobacteraceae Campylobacter.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_CAMJE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL139075 | CAB75271.1 | - |
| PIR | B81412 | B81412. | |
| GenomeReviews | AL111168_GR | Cj0635.1 | |
| BioCyc | CJEJ192222:CJ0635-MONOMER | -.1 | |
| LinkHub | Q9PHN2 | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 11168;
RX MEDLINE=20150912; PubMed=10688204; DOI=10.1038/35001088;
RA Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M.,
RA Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S.,
RA Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W.,
RA Quail M.A., Rajandream M.A., Rutherford K.M., van Vliet A.H.M.,
RA Whitehead S., Barrell B.G.;
RT "The genome sequence of the food-borne pathogen Campylobacter jejuni
RT reveals hypervariable sequences.";
RL Nature 403:665-668(2000).
Feature:
CHAIN 1 127 Putative Holliday junction resolvase.
/FTId=PRO_0000172039.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 127
MRALALDVGL KRIGVALCID KKIALPLDAV LRKNRNQAAN EIKNLLKIHE ISLLIVGIPK
GGSSEEEMTR RIKHFVSLLE FDKEICFVDE SGTSKEALGY GVANTRKKDG KLDSLSAFIM
IKDYFAL