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Description:
Protein recA (Recombinase A).
Molecular weight: 37430
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
01-FEB-1996, sequence version 1.
07-MAR-2006, entry version 37.
Phylogenetic order:
Bacteria Firmicutes Mollicutes Mycoplasmataceae Mycoplasma.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECA_MYCGE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | L43967 | AAC71564.1 | - |
| EMBL | U01704 | AAB01016.1 | - |
| PIR | E64237 | E64237. | |
| HSSP | P03017 | 2REB | |
| GenomeReviews | L43967_GR | MG339.1 | |
| TIGR | MG339 | -. | |
| BioCyc | MGEN2097:MG339-MONOMER | -.1 | |
| HAMAP | MF_00268 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001553 | RecA_bac. | |
| Pfam | PF00154 | RecA | 1. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02012 | tigrfam_recA | 1. |
| PROSITE | PS00321 | RECA_1 | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33530 / G-37;
RX MEDLINE=96026346; PubMed=7569993;
RA Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT "The minimal gene complement of Mycoplasma genitalium.";
RL Science 270:397-403(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 32-124.
RC STRAIN=ATCC 33530 / G-37;
RX MEDLINE=94075230; PubMed=8253680;
RA Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT "A survey of the Mycoplasma genitalium genome by using random
RT sequencing.";
RL J. Bacteriol. 175:7918-7930(1993).
Feature:
CHAIN 1 340 Protein recA.
/FTId=PRO_0000122758.
NP_BIND 67 74 ATP (By similarity).
CONFLICT 32 36 AKKNS -> CKEKH (in Ref. 2).
Comments:
-!- FUNCTION: Can catalyze the hydrolysis of ATP in the presence of
single-stranded DNA, the ATP-dependent uptake of single-stranded
DNA by duplex DNA, and the ATP-dependent hybridization of
homologous single-stranded DNAs. It interacts with lexA causing
its activation and leading to its autocatalytic cleavage.
-!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
-!- SIMILARITY: Belongs to the recA family.
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Sequence length: 340
MAQKEIINKK NTQKNSSFIE SNNLTSFDFF DAKKNSEIET ISTGSLNLDE ALGSGGLPLG
RIVELYGNES SGKTTIALNA VASFQKAGKT ACYIDAEGAL DLAYAKSIGI DLNKLLIAHP
RHGENAFALI ESLIKTNKIS LIVIDSVAAL IPKQELEGTI EEQTIGLHAR MMSKGLRRIQ
SILPDSKTCV LFINQLREKP GVMFGNNEVT TGGKALRFYS SLRMEAKRVE LLKDKFNNYV
GIKTKVMVSK NKIAKPFGVA ILEIMFNRGF VHEHEVIDLA LKFNVVVRAG NSYSFNNESI
AVGKEKLLNV LSEKPALFEQ IKELTVQQLA NKNSFQQTAS