Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 15936
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
01-DEC-2000, sequence version 1.
07-MAR-2006, entry version 27.
Phylogenetic order:
Bacteria Firmicutes Mollicutes Mycoplasmataceae Mycoplasma.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_MYCPN:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U00089 | AAG34748.1 | - |
| GenomeReviews | U00089_GR | MPN418.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29342 / M129;
RX MEDLINE=97105885; PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C.,
RA Herrmann R.;
RT "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT pneumoniae.";
RL Nucleic Acids Res. 24:4420-4449(1996).
RN [2]
RP IDENTIFICATION.
RX MEDLINE=20411492; PubMed=10954595; DOI=10.1093/nar/28.17.3278;
RA Dandekar T., Huynen M., Regula J.T., Ueberle B., Zimmermann C.U.,
RA Andrade M.A., Doerks T., Sanchez-Pulido L., Snel B., Suyama M.,
RA Yuan Y.P., Herrmann R., Bork P.;
RT "Re-annotating the Mycoplasma pneumoniae genome sequence: adding
RT value, function and reading frames.";
RL Nucleic Acids Res. 28:3278-3288(2000).
Feature:
CHAIN 1 140 Putative Holliday junction resolvase.
/FTId=PRO_0000172098.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 140
MQYILGIDFG LKRIGTALVN TIDRFPSPFR VFAVQNNLQQ AVNTLFKDLK QAGYELVQIV
IGFPHFHYQS SIQVSIHKFV ELIKTRFNVP VTLIDESGTT SEVKANLQEL GLKNRTFKKA
KDTLAATLIL ERFLNQQKPN