Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 15256
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-JAN-1998, sequence version 1.
07-MAR-2006, entry version 28.
Phylogenetic order:
Bacteria Proteobacteria Epsilonproteobacteria Campylobacterales Helicobacteraceae Helicobacter.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_HELPY:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000511 | AAD07403.1 | - |
| PIR | F64561 | F64561. | |
| GenomeReviews | AE000511_GR | HP0334.1 | |
| TIGR | HP0334 | -. | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=26695 / ATCC 700392;
RX MEDLINE=97394467; PubMed=9252185; DOI=10.1038/41483;
RA Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R.,
RA Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F.,
RA Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G.,
RA Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D.,
RA Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D.,
RA Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C.,
RA Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D.,
RA Smith H.O., Fraser C.M., Venter J.C.;
RT "The complete genome sequence of the gastric pathogen Helicobacter
RT pylori.";
RL Nature 388:539-547(1997).
Feature:
CHAIN 1 134 Putative Holliday junction resolvase.
/FTId=PRO_0000172073.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 134
MILACDVGLK RIGIAALLNG VILPLEAILR HNRNQASRDL SDLLREKNIQ VLVVGKPHES
YADTNARIEH FIKLVDFKGE IVFINEDRSS IEAYENLEHL GKKNKRLAIK DGRLDSLSAC
RILERYCQKV LKNH