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Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 16904
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
16-JUN-2003, sequence version 2.
07-MAR-2006, entry version 17.
Phylogenetic order:
Bacteria Actinobacteria Actinobacteridae Bifidobacteriales Bifidobacteriaceae Bifidobacterium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_BIFLO:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE014295 | AAN24694.1 | ALT_INIT |
| GenomeReviews | AE014295_GR | BL0881.1 | |
| BioCyc | BLON206672:BL0881-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCC 2705;
RX MEDLINE=22294977; PubMed=12381787; DOI=10.1073/pnas.212527599;
RA Schell M.A., Karmirantzou M., Snel B., Vilanova D., Berger B.,
RA Pessi G., Zwahlen M.-C., Desiere F., Bork P., Delley M.,
RA Pridmore R.D., Arigoni F.;
RT "The genome sequence of Bifidobacterium longum reflects its adaptation
RT to the human gastrointestinal tract.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:14422-14427(2002).
Feature:
CHAIN 1 152 Putative Holliday junction resolvase.
/FTId=PRO_0000172027.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 152
MVWLGVDLGN ARVGLALSDP ELTFAHPAGN IHVAGDYFFA IDEVLNVIED EHVDHVIVGL
PLQMDGTEGK SAKKARRWAA NLEKRLQAES EDSDSTEYQI PQVSLIDERL TTVSAHRQLF
EAHKASNKHR PVVDQQSAVV ILQTALDRTR EQ