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Description:
DNA repair and recombination protein radB.
Molecular weight: 24936
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
01-JAN-1998, sequence version 1.
07-MAR-2006, entry version 33.
Phylogenetic order:
Archaea Euryarchaeota Archaeoglobi Archaeoglobales Archaeoglobaceae Archaeoglobus.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADB_ARCFU:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE000782 | AAB89159.1 | - |
| PIR | H69511 | H69511. | |
| HSSP | Q06609 | 1N0W | |
| GenomeReviews | AE000782_GR | AF2096.1 | |
| TIGR | AF2096 | -. | |
| BioCyc | AFUL2234:AF2096-MONOMER | -.1 | |
| HAMAP | MF_00350 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| InterPro | IPR011939 | Recomb_radB. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR02237 | recomb_radB | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VC-16 / DSM 4304 / ATCC 49558;
RX MEDLINE=98049343; PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E.,
RA Ketchum K.A., Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D.,
RA Richardson D.L., Kerlavage A.R., Graham D.E., Kyrpides N.C.,
RA Fleischmann R.D., Quackenbush J., Lee N.H., Sutton G.G., Gill S.R.,
RA Kirkness E.F., Dougherty B.A., McKenney K., Adams M.D., Loftus B.J.,
RA Peterson S.N., Reich C.I., McNeil L.K., Badger J.H., Glodek A.,
RA Zhou L., Overbeek R., Gocayne J.D., Weidman J.F., McDonald L.A.,
RA Utterback T.R., Cotton M.D., Spriggs T., Artiach P., Kaine B.P.,
RA Sykes S.M., Sadow P.W., D'Andrea K.P., Bowman C., Fujii C.,
RA Garland S.A., Mason T.M., Olsen G.J., Fraser C.M., Smith H.O.,
RA Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-
RT reducing archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
Feature:
CHAIN 1 221 DNA repair and recombination protein
radB.
/FTId=PRO_0000150111.
NP_BIND 31 38 ATP (Potential).
Comments:
-!- FUNCTION: Involved in DNA repair and in homologous recombination.
May regulate the cleavage reactions of the branch-structured DNA.
Has a very weak ATPase activity that is not stimulated by DNA.
Binds DNA but does not promote DNA strands exchange (By
similarity).
-!- SIMILARITY: Belongs to the eukaryotic recA-like protein family.
RadB subfamily.
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Sequence length: 221
MQRMLIPTGS KCIDSLLGGG VETGTVTQIY GHGGTGKTTL CLMLAKNAAE QFKVAYIDTE
GLSGERVRQI FGDERLFSNV FVYEVYRFRQ QGVAIQEAEK LCRSEKVKLV IVDCFTSLYR
SELEDDRKQI KIKRELTSQL TFLLGMARKY DVAVVITNQM FTDVGSGVDR PLGGPSLEHL
SKVIIALERS NELRKATLIK HRWMKEGKSC FYRITDRGIE P