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Description:
DNA repair and recombination protein radA.
Molecular weight: 35467
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
27-APR-2001, integrated into UniProtKB/Swiss-Prot.
01-MAR-2001, sequence version 1.
07-MAR-2006, entry version 26.
Phylogenetic order:
Archaea Euryarchaeota Thermoplasmata Thermoplasmatales Thermoplasmataceae Thermoplasma.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_THEAC:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL445066 | CAC12231.1 | - |
| HSSP | Q06609 | 1N0W | |
| GenomeReviews | AL139299_GR | Ta1104.1 | |
| BioCyc | TACI2303:TA1104-MONOMER | -.1 | |
| HAMAP | MF_00348 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR000445 | HhH. | |
| InterPro | IPR003583 | HHH1_bd. | |
| InterPro | IPR001553 | RecA_bac. | |
| InterPro | IPR011938 | Recomb_radA. | |
| Pfam | PF00633 | HHH | 2. |
| PRINTS | PR00142 | RECA. | |
| ProDom | PD000229 | RecA | 1. |
| SMART | SM00382 | AAA | 1. |
| SMART | SM00278 | HhH1 | 2. |
| TIGRFAMs | TIGR02236 | recomb_radA | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
| PROSITE | PS50163 | RECA_3 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1728;
RX MEDLINE=20479972; PubMed=11029001; DOI=10.1038/35035069;
RA Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT acidophilum.";
RL Nature 407:508-513(2000).
Feature:
CHAIN 1 323 DNA repair and recombination protein
radA.
/FTId=PRO_0000150109.
NP_BIND 115 122 ATP (Potential).
Comments:
-!- FUNCTION: Involved in DNA repair and in homologous recombination.
Binds and assemble on single-stranded DNA to form a nucleoprotein
filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes
DNA strand exchange between homologous DNA molecules (By
similarity).
-!- SIMILARITY: Belongs to the eukaryotic recA-like protein family.
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Sequence length: 323
MMESNEENRE KKTIEDLPGV GEATAEKLRE NGYDDIMAIA VASPKDLSDV TGIGEGAAAK
IIAAARKFAD IGNFETGEEI LERRKSIQKL TTGSKNLDDL LGGGLETQAI TEFFGEFGSG
KTQIMHQLAV NCTLPKEKGG FDSDVMMIDT ENTFRPERII QMAKSKGADP DETLKRIHVA
RAYNSHHQIL LAEKAQDTAK EYNIKLLIVD SLTAHFRSEY VGRGSLAERQ QLLNKHMHDL
LRFGTIYNAV IAVTNQVSAR PDVFFGDPMA PIGGNIVGHT ATFRIYLRKS KGGKRIARLI
DSPYLPEGET VIQISEEGVS DGT