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Description:
DNA repair and recombination protein radB.
Molecular weight: 25309
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
27-APR-2001, integrated into UniProtKB/Swiss-Prot.
27-APR-2001, sequence version 2.
07-MAR-2006, entry version 26.
Phylogenetic order:
Archaea Euryarchaeota Thermoplasmata Thermoplasmatales Thermoplasmataceae Thermoplasma.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADB_THEAC:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL445066 | CAC12165.1 | ALT_INIT |
| HSSP | Q06609 | 1N0W | |
| GenomeReviews | AL139299_GR | Ta1036.1 | |
| BioCyc | TACI2303:TA1036-MONOMER | -.1 | |
| HAMAP | MF_00350 | - | 1. |
| InterPro | IPR001553 | RecA_bac. | |
| InterPro | IPR011939 | Recomb_radB. | |
| ProDom | PD000229 | RecA | 1. |
| TIGRFAMs | TIGR02237 | recomb_radB | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 1728;
RX MEDLINE=20479972; PubMed=11029001; DOI=10.1038/35035069;
RA Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT acidophilum.";
RL Nature 407:508-513(2000).
Feature:
CHAIN 1 229 DNA repair and recombination protein
radB.
/FTId=PRO_0000150120.
NP_BIND 38 45 ATP (Potential).
Comments:
-!- FUNCTION: Involved in DNA repair and in homologous recombination.
May regulate the cleavage reactions of the branch-structured DNA.
Has a very weak ATPase activity that is not stimulated by DNA.
Binds DNA but does not promote DNA strands exchange (By
similarity).
-!- SIMILARITY: Belongs to the eukaryotic recA-like protein family.
RadB subfamily.
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Sequence length: 229
MDEISLQQGV RRIQTGVGCI DALLNGGLEG GIITEIFGEG GSGKTNICMI ASCSAMSQGL
KVIYIDSEGL SPERFLAVCR SDISMFKLFR VYSLDDQEVA IMKASKMADR DQKIGMIVLD
SFSEFFRLEK SDDRQARIAE FQRQLSLLSS VAAKKNIPVL ITNQIYQDID NGTLLPFGGF
LVDHAMKAIL RIEKMPDGRR RITVTKHRSV REGVSAMFRI TDDGVSCEG