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Description:
Holliday junction ATP-dependent DNA helicase ruvA (EC 3.6.1.-).
Molecular weight: 20920
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
01-OCT-2000, sequence version 1.
07-MAR-2006, entry version 33.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Xanthomonadales Xanthomonadaceae Xylella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVA_XYLFA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE004010 | AAF84710.1 | - |
| PIR | G82623 | G82623. | |
| HSSP | P08576 | 1CUK | |
| GenomeReviews | AE003849_GR | Xf1904.1 | |
| HAMAP | MF_00031 | - | 1. |
| InterPro | IPR000445 | HhH. | |
| InterPro | IPR003583 | HHH1_bd. | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR000085 | RuvA. | |
| InterPro | IPR011114 | RuvA_C. | |
| Pfam | PF00633 | HHH | 2. |
| Pfam | PF07499 | RuvA_C | 1. |
| Pfam | PF01330 | RuvA_N | 1. |
| ProDom | PD006268 | RuvA | 1. |
| SMART | SM00278 | HhH1 | 2. |
| TIGRFAMs | TIGR00084 | ruvA | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Helicase; Hydrolase; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9a5c;
RX MEDLINE=20365717; PubMed=10910347; DOI=10.1038/35018003;
RA Simpson A.J.G., Reinach F.C., Arruda P., Abreu F.A., Acencio M.,
RA Alvarenga R., Alves L.M.C., Araya J.E., Baia G.S., Baptista C.S.,
RA Barros M.H., Bonaccorsi E.D., Bordin S., Bove J.M., Briones M.R.S.,
RA Bueno M.R.P., Camargo A.A., Camargo L.E.A., Carraro D.M., Carrer H.,
RA Colauto N.B., Colombo C., Costa F.F., Costa M.C.R., Costa-Neto C.M.,
RA Coutinho L.L., Cristofani M., Dias-Neto E., Docena C., El-Dorry H.,
RA Facincani A.P., Ferreira A.J.S., Ferreira V.C.A., Ferro J.A.,
RA Fraga J.S., Franca S.C., Franco M.C., Frohme M., Furlan L.R.,
RA Garnier M., Goldman G.H., Goldman M.H.S., Gomes S.L., Gruber A.,
RA Ho P.L., Hoheisel J.D., Junqueira M.L., Kemper E.L., Kitajima J.P.,
RA Krieger J.E., Kuramae E.E., Laigret F., Lambais M.R., Leite L.C.C.,
RA Lemos E.G.M., Lemos M.V.F., Lopes S.A., Lopes C.R., Machado J.A.,
RA Machado M.A., Madeira A.M.B.N., Madeira H.M.F., Marino C.L.,
RA Marques M.V., Martins E.A.L., Martins E.M.F., Matsukuma A.Y.,
RA Menck C.F.M., Miracca E.C., Miyaki C.Y., Monteiro-Vitorello C.B.,
RA Moon D.H., Nagai M.A., Nascimento A.L.T.O., Netto L.E.S.,
RA Nhani A. Jr., Nobrega F.G., Nunes L.R., Oliveira M.A.,
RA de Oliveira M.C., de Oliveira R.C., Palmieri D.A., Paris A.,
RA Peixoto B.R., Pereira G.A.G., Pereira H.A. Jr., Pesquero J.B.,
RA Quaggio R.B., Roberto P.G., Rodrigues V., de Rosa A.J.M.,
RA de Rosa V.E. Jr., de Sa R.G., Santelli R.V., Sawasaki H.E.,
RA da Silva A.C.R., da Silva A.M., da Silva F.R., Silva W.A. Jr.,
RA da Silveira J.F., Silvestri M.L.Z., Siqueira W.J., de Souza A.A.,
RA de Souza A.P., Terenzi M.F., Truffi D., Tsai S.M., Tsuhako M.H.,
RA Vallada H., Van Sluys M.A., Verjovski-Almeida S., Vettore A.L.,
RA Zago M.A., Zatz M., Meidanis J., Setubal J.C.;
RT "The genome sequence of the plant pathogen Xylella fastidiosa.";
RL Nature 406:151-159(2000).
Feature:
CHAIN 1 194 Holliday junction ATP-dependent DNA
helicase ruvA.
/FTId=PRO_0000094714.
Comments:
-!- FUNCTION: The ruvA-ruvB complex in the presence of ATP renatures
cruciform structure in supercoiled DNA with palindromic sequence,
indicating that it may promote strand exchange reactions in
homologous recombination. RuvAB is an helicase that mediates the
Holliday junction migration by localized denaturation and
reannealing. RuvA stimulates, in the presence of DNA, the weak
ATPase activity of ruvB (By similarity).
-!- SUBUNIT: Forms a complex with ruvB.
-!- SIMILARITY: Belongs to the ruvA family.
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Sequence length: 194
MIGRLRGVLT SKTPPWLVVD VCGVGYELEV PMSTFYELPN VGYEVNLFTH YTQKDDSAAL
YGFLSESERR LFRHLQRVSG IGTKIALAVL SSVSVDTFAG LIQAGDVNAL TVIPGIGKKT
AERMLVELRD RAADFNNGIS TSGKLNLDTV SEAALALQQL GYKPAEAARM ARDAGTESDD
VASVIKKALQ AALR