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Description:
DNA repair protein radA homolog (DNA repair protein sms homolog).
Molecular weight: 48411
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
08-DEC-2000, sequence version 2.
07-MAR-2006, entry version 42.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_PSEAE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | U89384 | AAB49466.1 | - |
| EMBL | AE004875 | AAG07997.1 | - |
| PIR | A83069 | A83069. | |
| GenomeReviews | AE004091_GR | PA4609.1 | |
| BioCyc | PAER287:PA4609-MONOMER | -.1 | |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001984 | Peptidase_S16. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00830 | ENDOLAPTASE. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=FRD1;
RA Howell M.L., Heur M., Klotz M.G., Hassett D.J.;
RT "Pseudomonas aeruginosa oxidative stress operon.";
RL Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / PAO1;
RX MEDLINE=20437337; PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T.,
RA Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an
RT opportunistic pathogen.";
RL Nature 406:959-964(2000).
Feature:
CHAIN 1 453 DNA repair protein radA homolog.
/FTId=PRO_0000187934.
ZN_FING 10 27 C4-type (Potential).
NP_BIND 96 103 ATP (Potential).
CONFLICT 142 142 E -> K (in Ref. 1).
CONFLICT 240 240 E -> D (in Ref. 1).
CONFLICT 243 244 GR -> AA (in Ref. 1).
CONFLICT 247 247 L -> M (in Ref. 1).
CONFLICT 258 258 V -> F (in Ref. 1).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage (By similarity).
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
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Sequence length: 453
MAKAKRMYGC TECGATFPKW AGQCADCGAW NTLVETVVEA APSGSGRGGW AGQQANLKTL
AEVSVEEMPR FTTGSTELDR VLGGGLVDGS VVLIGGDPGI GKSTILLQTL CNLASRVPAL
YVTGEESQQQ VAMRARRLSL PEDKLKVMTE TSIETIIATA RQEQPRVMVI DSIQTIFTEQ
LQSAPGGVAQ VRESAAMLVR YAKQSGTAIF LVGHVTKEGA LAGPRVLEHM VDTVLYFEGE
SDGRLRLLRA VKNRFGAVNE LGVFGMTDKG LKEVSNPSAI FLTRAQEAVP GSVVMATWEG
SRPMLVEVQA LVDTSHLANP RRVTLGLDQN RLAMLLAVLH RHGGIPTYDQ DVFLNVVGGV
KVLETASDLA LMAAVMSSLR NRPLPHDLLV FGEVGLSGEV RPVPSGQERL KEAGKHGFKR
AIVPLGNAPK EAPAGLQVIA VTRLEQALDA LFE