|
|
|
|
|
|
Description:
Single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein).
Molecular weight: 18426
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
24-OCT-2003, sequence version 2.
07-MAR-2006, entry version 47.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB_PSEAE:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | Z32859 | CAA83688.1 | - |
| EMBL | AE004840 | AAG07620.1 | - |
| PIR | JC5485 | S44302. | |
| HSSP | P02339 | 1KAW | |
| SMR | P40947 | 1-117.1 | |
| GenomeReviews | AE004091_GR | PA4232.1 | |
| BioCyc | PAER287:PA4232-MONOMER | -.1 | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR011344 | Single_strand_bd. | |
| InterPro | IPR000424 | SSB_primosomal_n. | |
| InterPro | IPR010913 | ssDNA_bd. | |
| Pfam | PF00436 | SSB | 1. |
| TIGRFAMs | TIGR00621 | ssb | 1. |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; Direct protein sequencing; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-37 AND 51-62,
RP AND SUBUNIT.
RC STRAIN=PAO / DSM 1707;
RX MEDLINE=97136702; PubMed=8982079; DOI=10.1016/S0378-1119(96)00535-5;
RA Genschel J., Litz L., Thole H., Roemling U., Urbanke C.;
RT "Isolation, sequencing and overproduction of the single-stranded DNA
RT binding protein from Pseudomonas aeruginosa PAO.";
RL Gene 182:137-143(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / PAO1;
RX MEDLINE=20437337; PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T.,
RA Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an
RT opportunistic pathogen.";
RL Nature 406:959-964(2000).
Feature:
INIT_MET 0 0
CHAIN 1 164 Single-stranded DNA-binding protein.
/FTId=PRO_0000096078.
DOMAIN 4 109 SSB.
DNA_BIND 53 59 By similarity.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosome. It is also involved in DNA recombination and repair
(By similarity).
-!- SUBUNIT: Homotetramer.
-!- SIMILARITY: Contains 1 SSB domain.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 164
ARGVNKVILV GNVGGDPETR YMPNGNAVTN ITLATSESWK DKQTGQQQER TEWHRVVFFG
RLAEIAGEYL RKGSQVYVEG SLRTRKWQGQ DGQDRYTTEI VVDINGNMQL LGGRPSGDDS
QRAPREPMQR PQQAPQQQSR PAPQQQPAPQ PAQDYDSFDD DIPF