Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 17555
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-MAR-2002, sequence version 1.
07-MAR-2006, entry version 20.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rhizobiales Brucellaceae Brucella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_BRUME:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE009702 | AAL53914.1 | - |
| PIR | AG3593 | AG3593. | |
| GenomeReviews | AE008918_GR | BMEII0672.1 | |
| BioCyc | BMEL29459:BMEII0672-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=16M / ATCC 23456 / Biotype 1;
RX MEDLINE=20020109; PubMed=11756688; DOI=10.1073/pnas.221575398;
RA DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA Haselkorn R., Kyrpides N.C., Overbeek R.;
RT "The genome sequence of the facultative intracellular pathogen
RT Brucella melitensis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
Feature:
CHAIN 1 162 Putative Holliday junction resolvase.
/FTId=PRO_0000172032.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 162
MATAEIEEIP ALLKPGQTVA GLDLGTKTIG LAVSDLGLSF AHPRPVIKRV KFTIDAQVLL
KALETDKVGV IVIGLPMNMD GTAGPRVQAT RAFVRTMQPL TDLPFVFWDE RLSTVAVERA
LIGMDVSRGK RADRIDSAAA AFILQGALDR LHMMRRNDYD AG