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Description:
DNA mismatch repair protein mutS.
Molecular weight: 95201
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
01-JUN-2003, sequence version 1.
07-MAR-2006, entry version 21.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein MUTS_PSESM:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AE016853 | AAO57515.1 | - |
| HSSP | P23909 | 1NG9 | |
| GenomeReviews | AE016853_GR | PSPTO4058.1 | |
| TIGR | PSPTO4058 | -. | |
| BioCyc | PSYR223283:PSPTO4058-MONOMER | -.1 | |
| HAMAP | MF_00096 | - | 1. |
| InterPro | IPR005748 | MutS1. | |
| InterPro | IPR000432 | MutS_C. | |
| InterPro | IPR007860 | MutS_II. | |
| InterPro | IPR007696 | MutS_III. | |
| InterPro | IPR007861 | MutS_IV. | |
| InterPro | IPR007695 | MutS_N. | |
| PANTHER | PTHR11361:SF23 | MutS.1 | 1. |
| Pfam | PF01624 | MutS_I | 1. |
| Pfam | PF05188 | MutS_II | 1. |
| Pfam | PF05192 | MutS_III | 1. |
| Pfam | PF05190 | MutS_IV | 1. |
| Pfam | PF00488 | MutS_V | 1. |
| ProDom | PD001263 | MutS_C | 1. |
| SMART | SM00534 | MUTSac | 1. |
| SMART | SM00533 | MUTSd | 1. |
| TIGRFAMs | TIGR01070 | mutS1 | 1. |
| PROSITE | PS00486 | DNA_MISMATCH_REPAIR_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DC3000;
RX MEDLINE=22834015; PubMed=12928499; DOI=10.1073/pnas.1731982100;
RA Buell C.R., Joardar V., Lindeberg M., Selengut J., Paulsen I.T.,
RA Gwinn M.L., Dodson R.J., DeBoy R.T., Durkin A.S., Kolonay J.F.,
RA Madupu R., Daugherty S.C., Brinkac L.M., Beanan M.J., Haft D.H.,
RA Nelson W.C., Davidsen T.M., Zafar N., Zhou L., Liu J., Yuan Q.,
RA Khouri H.M., Fedorova N.B., Tran B., Russell D., Berry K.J.,
RA Utterback T.R., Van Aken S.E., Feldblyum T.V., D'Ascenzo M.,
RA Deng W.-L., Ramos A.R., Alfano J.R., Cartinhour S., Chatterjee A.K.,
RA Delaney T.P., Lazarowitz S.G., Martin G.B., Schneider D.J., Tang X.,
RA Bender C.L., White O., Fraser C.M., Collmer A.;
RT "The complete genome sequence of the Arabidopsis and tomato pathogen
RT Pseudomonas syringae pv. tomato DC3000.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:10181-10186(2003).
Feature:
CHAIN 1 855 DNA mismatch repair protein mutS.
/FTId=PRO_0000115123.
NP_BIND 613 620 ATP (Potential).
Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
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Sequence length: 855
MTDLSQHTPM MQQYWKLKNQ HLDQLMFYRM GDFYEIFYED AKKAAKLLDI TLTARGQSAG
QSIPMCGIPY HAAEGYLAKL VKLGESVVIC EQIGDPATSK GPVDRQVVRI ITPGTISDEA
LLDERRDNLI AAVLGDERLF GLAVLDITSG NFSVLEIKGW ENLLAELERI NPVELLIPDD
WPQGLPAEKR RGARRRAPWD FERDSAHKSL CQQFSTQDLK GFGCETLTLA IGAAGCLLGY
AKETQRTALP HLRSLRHERL DDTVILDAAS RRNLELDTNL SGGRDNTLQS VMDRCQTAMG
TRLLTRWLNR PLRDLSILQA RQTSITCFLE RYRFENLQPQ LKEIGDIERI LARIGLRNAR
PRDLARLRDA LSALPELQQA MTDLDAPHLQ QLAQTASTYP ELADLLQRAI NDNPPAVIRD
GGVLKTGYDA ELDELQSLSE NAGQFLIDLE AREKARTGLS HLKVGYNRVH GYFIELPSKQ
AEQAPADYIR RQTLKGAERF ITPELKEFED KALSAKSRAL AREKMLYETL LEDLIGHLAP
LQDTAAALAE LDVLSNLAER ALNLDLNCPR FVAEPCMRIE QGRHPVVEQV LSTPFVANDL
ALDDSTRMLI ITGPNMGGKS TYMRQTALIV LLAHIGSFVP AASCELSLVD RIFTRIGSSD
DLAGGRSTFM VEMSETANIL HNATDKSLVL MDEVGRGTST FDGLSLAWAA AECLAQLRAY
TLFATHYFEL TVLPESEPLV NNVHLNATEH NERIVFLHRV LPGPASQSYG LAVAQLAGVP
GKVITRAKEH LQRLETTSLP HEQPRAKPGK PAIPQQSDMF ASLPHPVLDE LSKIKVDDMT
PRQALDLLYT LQTRL