Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 16583
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
01-MAR-2003, sequence version 1.
07-MAR-2006, entry version 17.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Wigglesworthia.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_WIGBR:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000021 | BAC24310.1 | - |
| GenomeReviews | BA000021_GR | WIGBR1640.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX MEDLINE=22297718; PubMed=12219091; DOI=10.1038/ng986;
RA Akman L., Yamashita A., Watanabe H., Oshima K., Shiba T., Hattori M.,
RA Aksoy S.;
RT "Genome sequence of the endocellular obligate symbiont of tsetse
RT flies, Wigglesworthia glossinidia.";
RL Nat. Genet. 32:402-407(2002).
Feature:
CHAIN 1 144 Putative Holliday junction resolvase.
/FTId=PRO_0000172174.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 144
MMYRNNLLIS FDFGTKNIGV AIGQMKTNTS KPLESVSYVK GVPNWGKINN IILLWEPKYI
IVGLPLNMDG SYQTSTIKAK KFAKQLRNKF FMPVMMHDER LTTIEAKSVL FKKYGYKGLK
KKLIDSESAV IILDSWMNSI YFKK