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Description:
Holliday junction ATP-dependent DNA helicase ruvB (EC 3.6.1.-).
Molecular weight: 38087
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
01-JUN-2003, sequence version 1.
07-MAR-2006, entry version 21.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rhizobiales Bradyrhizobiaceae Bradyrhizobium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVB_BRAJA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000040 | BAC46802.1 | - |
| HSSP | Q56313 | 1IN4 | |
| GenomeReviews | BA000040_GR | blr1537.1 | |
| HAMAP | MF_00016 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR003959 | AAA_ATPase_centr. | |
| InterPro | IPR004605 | RuvB. | |
| InterPro | IPR008823 | RuvB_C. | |
| InterPro | IPR008824 | RuvB_N. | |
| InterPro | IPR011991 | Wing_hlx_DNA_bd. | |
| Pfam | PF00004 | AAA | 1. |
| Pfam | PF05491 | RuvB_C | 1. |
| Pfam | PF05496 | RuvB_N | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00635 | ruvB | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA repair; Helicase; Hydrolase; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USDA 110;
RX MEDLINE=22484998; PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T.,
RA Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K.,
RA Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M.,
RA Tabata S.;
RT "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT Bradyrhizobium japonicum USDA110.";
RL DNA Res. 9:189-197(2002).
Feature:
CHAIN 1 351 Holliday junction ATP-dependent DNA
helicase ruvB.
/FTId=PRO_0000165504.
NP_BIND 63 70 ATP (Potential).
Comments:
-!- FUNCTION: The ruvA-ruvB complex in the presence of ATP renatures
cruciform structure in supercoiled DNA with palindromic sequence,
indicating that it may promote strand exchange reactions in
homologous recombination. RuvAB is an helicase that mediates the
Holliday junction migration by localized denaturation and
reannealing (By similarity).
-!- SUBUNIT: Forms a complex with ruvA (By similarity).
-!- SIMILARITY: Belongs to the ruvB family.
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Sequence length: 351
MSDPKANRMV SPERRSDDVG DTALRPQSLS DFVGQQQARK NLSIFIEAAR KRGEALDHVL
FVGPPGLGKT TLAQIVAKEL GVGFRATSGP VIAKAGDLAA LLTNLEERDV LFIDEIHRLS
PAVEEVLYPA MEDFQLDLII GEGPAARSVK IELSKFTLVG ATTRAGLLTN PLRDRFGIPV
RLNFYTIEEL ESIVSRGARV LNVGMSADGA NEIARRARGT PRIAGRLLRR VRDFASAADA
DTIDRKIADH ALSALEVDAA GLDAMDRRYL TTIAMNYGGG PVGVETMAAA LSEPRDAIED
IIEPYLIQCG YLQRTPRGRL LTSHAFRHLG LAEPNRDAAQ FGLFGTDESD D