|
|
|
|
|
|
Description:
DNA mismatch repair protein mutS.
Molecular weight: 99182
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 ) mismatch repair( GO:0006298 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
30-MAY-2000, sequence version 1.
07-MAR-2006, entry version 34.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rhizobiales Rhizobiaceae Sinorhizobium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein MUTS_RHIME:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL591783 | CAC41832.1 | - |
| EMBL | AF227730 | AAF37851.1 | - |
| HSSP | P23909 | 1NG9 | |
| GenomeReviews | AL591688_GR | R00395.1 | |
| BioCyc | SMEL382:SMC01125-MONOMER | -.1 | |
| HAMAP | MF_00096 | - | 1. |
| InterPro | IPR005748 | MutS1. | |
| InterPro | IPR000432 | MutS_C. | |
| InterPro | IPR007860 | MutS_II. | |
| InterPro | IPR007696 | MutS_III. | |
| InterPro | IPR007861 | MutS_IV. | |
| InterPro | IPR007695 | MutS_N. | |
| PANTHER | PTHR11361:SF23 | MutS.1 | 1. |
| Pfam | PF01624 | MutS_I | 1. |
| Pfam | PF05188 | MutS_II | 1. |
| Pfam | PF05192 | MutS_III | 1. |
| Pfam | PF05190 | MutS_IV | 1. |
| Pfam | PF00488 | MutS_V | 1. |
| ProDom | PD001263 | MutS_C | 1. |
| SMART | SM00534 | MUTSac | 1. |
| SMART | SM00533 | MUTSd | 1. |
| TIGRFAMs | TIGR01070 | mutS1 | 1. |
| PROSITE | PS00486 | DNA_MISMATCH_REPAIR_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX MEDLINE=21396507; PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D.,
RA Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U.,
RA Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont
RT Sinorhizobium meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 566-916.
RX MEDLINE=21172888; PubMed=11274131;
RX DOI=10.1128/JB.183.8.2682-2685.2001;
RA Rudnick P.A., Arcondeguy T., Kennedy C.K., Kahn D.;
RT "glnD and mviN are genes of an essential operon in Sinorhizobium
RT meliloti.";
RL J. Bacteriol. 183:2682-2685(2001).
Feature:
CHAIN 1 916 DNA mismatch repair protein mutS.
/FTId=PRO_0000115126.
NP_BIND 665 672 ATP (Potential).
Comments:
-!- FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity (By similarity).
-!- SIMILARITY: Belongs to the DNA mismatch repair mutS family.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
Distributed under the Creative Commons Attribution-NoDerivs License
-----------------------------------------------------------------------
Sequence length: 916
MNFLMDASNR SGDVLSVSDL ASEESRSTAT PMMEQFIEIK ANNPDSLLFY RMGDFYELFF
QDAVEASRAL GITLTKRGQH MGQEIPMCGV PVHAADDYLQ KLIASGYRVA VCEQVEDPAE
AKKRGSKSVV RRDVVRLVTP GTITEDKLLS PSESNYLMAL ARIRSGSEPA YALAWIDIST
GIFRLAETAE SRLLADILRI EPRELILPDT VFHDPDLRPV FDVLGRVAVP QPAVLFDSAT
AEGRISRYYG VGTLDGFGSF SRAELAAASA AVSYVEKTQL QERPALGIPE RESAASTLFI
DPATRANLEL AKTLSGSRDG SLLKSLDRTM TSGGARLLAE RLMSPLTDPE RINQRLDSIE
VLADQPRFTT DVRDALRRAP DMPRALSRLA LGRGGPRDLG AIQAGMRAAA AISALLSGAE
LSAELTEARD AIAALPGELL ARLDATLAEE LPLLKRDGGF VREGASAELD EMRALRDQSR
RVIAGLQLQY CEETGIKSLK IKHNNVLGYF IEVTAGNAGS MTDTDAGRAR FIHRQTMANA
MRFTTTELAE LETKIANAAD RALAIELETF EAMVREVVAE AEAIKAAALA LATIDVSAGL
AVLAEEQNYT RPTVDRSRMF AIDGGRHPVV EQALRRQAAN PFVANGCDLS PPNGEQGGAI
WLLTGPNMGG KSTFLRQNAL IAIMAQTGSF VPAAAAHIGV VDRLFSRVGA SDDLARGRST
FMVEMVETAA ILNQATDRSL VILDEIGRGT ATFDGLSIAW AAVEHLHEVN RCRGLFATHF
HELTVLSEKL VRLSNATMRV KEWDGDVIFL HEVGPGAADR SYGIQVARLA GLPASVVARA
RDVLAKLEDA DRKNPASQLI DDLPLFQVAV RREEAARASS GPSKVEEALK ALNPDDMTPR
EALDALYALK KELSNR