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Description:
DNA replication and repair protein recF.
Molecular weight: 40596
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
30-MAY-2000, sequence version 1.
07-MAR-2006, entry version 34.
Phylogenetic order:
Bacteria Proteobacteria Alphaproteobacteria Rhizobiales Rhizobiaceae Sinorhizobium.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECF_RHIME:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AL591782 | CAC41575.1 | - |
| EMBL | AF008187 | AAB70169.2.1 | - |
| GenomeReviews | AL591688_GR | R00188.1 | |
| BioCyc | SMEL382:SMC02863-MONOMER | -.1 | |
| HAMAP | MF_00365 | - | 1. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001238 | RecF. | |
| InterPro | IPR003395 | SMC_N. | |
| Pfam | PF02463 | SMC_N | 1. |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00611 | recf | 1. |
| PROSITE | PS00617 | RECF_1 | 1. |
| PROSITE | PS00618 | RECF_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; Nucleotide-binding; SOS response.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX MEDLINE=21396507; PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D.,
RA Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U.,
RA Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont
RT Sinorhizobium meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-176.
RC STRAIN=SU47 / 1021;
RX MEDLINE=98361913; PubMed=9696772;
RA Bardin S.D., Voegele R.T., Finan T.M.;
RT "Phosphate assimilation in Rhizobium (Sinorhizobium) meliloti:
RT identification of a pit-like gene.";
RL J. Bacteriol. 180:4219-4226(1998).
Feature:
CHAIN 1 374 DNA replication and repair protein recF.
/FTId=PRO_0000196448.
NP_BIND 34 41 ATP (Potential).
CONFLICT 169 176 RNRLLSEF -> ATGFSRNS (in Ref. 2).
Comments:
-!- FUNCTION: The recF protein is involved in DNA metabolism; it is
required for DNA replication and normal SOS inducibility. RecF
binds preferentially to single-stranded, linear DNA. It also seems
to bind ATP (By similarity).
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the recF family.
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Sequence length: 374
MPHKVFLTRL KLSDFRNYAT LALDLDQRHV VLTGENGAGK TNLMEGVSFL SPGRGLRRAA
YADVARVGAP DGFSVFAAVD GMEGSVEIGT GTQGTEEGQS RRLRINGTAA RTVDELTDHL
RVLWLTPAMD GLFTGPSADR RRFLDRLVLS LDPEHGRRAS EFDRAMRSRN RLLSEFRPDP
AWLSAIEREM AGLGISMALA RQEMLGLLSA LVERSRSDGT FPSASLSLAG FLDDCAGIPA
FELEERYLAM LAEGRARDAA AGRTLDGPHR SDLLIRHREK DIEAERCSTG EQKALLVGLV
LAHARLVGDM TGHAPVLLLD EIAAHLDQGR RAALFDLVDG LGGQSFMTGT DRAMFDALGE
RAQYLAVANG RVSG