Description:
DNA repair and recombination protein radB.
Molecular weight: 26009
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
01-OCT-2001, sequence version 1.
07-MAR-2006, entry version 22.
Phylogenetic order:
Archaea Euryarchaeota Thermoplasmata Thermoplasmatales Thermoplasmataceae Thermoplasma.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADB_THEVO:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BA000011 | BAB59700.1 | - |
| HSSP | Q06609 | 1N0W | |
| GenomeReviews | BA000011_GR | TV0558.1 | |
| HAMAP | MF_00350 | - | 1. |
| InterPro | IPR001553 | RecA_bac. | |
| InterPro | IPR011939 | Recomb_radB. | |
| ProDom | PD000229 | RecA | 1. |
| TIGRFAMs | TIGR02237 | recomb_radB | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA recombination; DNA-binding; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSS1 / DSM 4299 / JCM 9571;
RX MEDLINE=20570466; PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA Kawashima T., Amano N., Koike H., Makino S., Higuchi S.,
RA Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T.,
RA Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT "Archaeal adaptation to higher temperatures revealed by genomic
RT sequence of Thermoplasma volcanium.";
RL Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
Feature:
CHAIN 1 234 DNA repair and recombination protein
radB.
/FTId=PRO_0000150121.
Comments:
-!- FUNCTION: Involved in DNA repair and in homologous recombination.
May regulate the cleavage reactions of the branch-structured DNA.
Has a very weak ATPase activity that is not stimulated by DNA.
Binds DNA but does not promote DNA strands exchange (By
similarity).
-!- SIMILARITY: Belongs to the eukaryotic recA-like protein family.
RadB subfamily.
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Sequence length: 234
MMEEISLQEK IEKLPLGVAC IDGLTNGGLE AGIITEIFGE GGSGKSNVCM LAACSALRLG
KKVVFIDSEG FSSERFLSIC KADNSKLKVI RVFSLDDQEV AITKFSKIIE KDASYGLFIL
DSFSEFFRLE RTGDNQSRVI DFQRQLSLLS SIAAKRKIPV LITNQIYQDI ANGDILPFGG
YVVDHIMKAI YRLERLPDGR RKMTVMKHRS VKEGNSVEFR IVQDGISCEV KNGN