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Description:
Putative Holliday junction resolvase (EC 3.1.-.-).
Molecular weight: 14619
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
26-APR-2005, integrated into UniProtKB/Swiss-Prot.
01-OCT-2003, sequence version 1.
07-MAR-2006, entry version 18.
Phylogenetic order:
Bacteria Proteobacteria Betaproteobacteria Burkholderiales Alcaligenaceae Bordetella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RUVX_BORPA:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | BX640435 | CAE39214.1 | - |
| HSSP | P52050 | 1OVQ | |
| GenomeReviews | BX470249_GR | BPP3931.1 | |
| BioCyc | BPAR519:BPP3931-MONOMER | -.1 | |
| HAMAP | MF_00651 | - | 1. |
| InterPro | IPR005227 | HJR_YqgF. | |
| InterPro | IPR012337 | RNaseH_fold. | |
| InterPro | IPR006641 | YqgFc. | |
| Pfam | PF03652 | UPF0081 | 1. |
| SMART | SM00732 | YqgFc | 1. |
| TIGRFAMs | TIGR00250 | HJR_YqgF | 1. |
Keywords:
Complete proteome; DNA damage; DNA recombination; DNA repair; Hydrolase; Nuclease.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=12822 / ATCC BAA-587;
RX MEDLINE=22827954; PubMed=12910271; DOI=10.1038/ng1227;
RA Parkhill J., Sebaihia M., Preston A., Murphy L.D., Thomson N.R.,
RA Harris D.E., Holden M.T.G., Churcher C.M., Bentley S.D., Mungall K.L.,
RA Cerdeno-Tarraga A.-M., Temple L., James K.D., Harris B., Quail M.A.,
RA Achtman M., Atkin R., Baker S., Basham D., Bason N., Cherevach I.,
RA Chillingworth T., Collins M., Cronin A., Davis P., Doggett J.,
RA Feltwell T., Goble A., Hamlin N., Hauser H., Holroyd S., Jagels K.,
RA Leather S., Moule S., Norberczak H., O'Neil S., Ormond D., Price C.,
RA Rabbinowitsch E., Rutter S., Sanders M., Saunders D., Seeger K.,
RA Sharp S., Simmonds M., Skelton J., Squares R., Squares S., Stevens K.,
RA Unwin L., Whitehead S., Barrell B.G., Maskell D.J.;
RT "Comparative analysis of the genome sequences of Bordetella pertussis,
RT Bordetella parapertussis and Bordetella bronchiseptica.";
RL Nat. Genet. 35:32-40(2003).
Feature:
CHAIN 1 133 Putative Holliday junction resolvase.
/FTId=PRO_0000172029.
Comments:
-!- FUNCTION: Could be a nuclease that resolves Holliday junction
intermediates in genetic recombination.
-!- SUBCELLULAR LOCATION: Cytoplasm (Potential).
-!- SIMILARITY: Belongs to the yqgF HJR family.
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Sequence length: 133
MPEETLLAFD FGEKKIGIAI GNTLTRQARP LEIIFSETRA ARFGRIGQLL QEWQPQRAVV
GLPLTLDGQE QPASARARRF ANQLHGRFGL AVELVDERGS SMEAQQLLGT HAADDAVAAA
VILQRYLDTL PQP