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Description:
DNA repair protein radA (DNA repair protein sms).
Molecular weight: 49472
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
01-MAR-1992, sequence version 1.
07-MAR-2006, entry version 57.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Escherichia.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RADA_ECOLI:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | X63155 | CAA44856.1 | - |
| EMBL | U14003 | AAA97285.1 | - |
| EMBL | U00096 | AAC77342.1 | - |
| EMBL | U59449 | AAC44380.1 | - |
| PIR | JC1417 | JC1417. | |
| GenomeReviews | U00096_GR | b4389.1 | |
| EchoBASE | EB1273 | -.1 | |
| EcoGene | EG11296 | radA. | |
| BioCyc | EcoCyc:EG11296-MONOMER | -.1 | |
| GO | GO:0005515 | F:protein binding | IPI. |
| InterPro | IPR003593 | AAA_ATPase. | |
| InterPro | IPR001984 | Peptidase_S16. | |
| InterPro | IPR004504 | RadA. | |
| InterPro | IPR001553 | RecA_bac. | |
| PRINTS | PR01874 | DNAREPAIRADA. | |
| PRINTS | PR00830 | ENDOLAPTASE. | |
| SMART | SM00382 | AAA | 1. |
| TIGRFAMs | TIGR00416 | sms | 1. |
| PROSITE | PS50162 | RECA_2 | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; DNA-binding; Metal-binding; Nucleotide-binding; Zinc; Zinc-finger.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX MEDLINE=93013006; PubMed=1327967; DOI=10.1016/0378-1119(92)90002-7;
RA Neuwald A.F., Berg D.E., Stauffer G.V.;
RT "Mutational analysis of the Escherichia coli serB promoter region
RT reveals transcriptional linkage to a downstream gene.";
RL Gene 120:1-9(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / MG1655;
RX MEDLINE=95334362; PubMed=7610040;
RA Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.,
RA Blattner F.R.;
RT "Analysis of the Escherichia coli genome VI: DNA sequence of the
RT region from 92.8 through 100 minutes.";
RL Nucleic Acids Res. 23:2105-2119(1995).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / AB1157;
RX MEDLINE=96326357; PubMed=8759876;
RA Song Y., Sargentini N.J.;
RT "Escherichia coli DNA repair genes radA and sms are the same gene.";
RL J. Bacteriol. 178:5045-5048(1996).
Feature:
CHAIN 1 460 DNA repair protein radA.
/FTId=PRO_0000187926.
ZN_FING 11 28 C4-type (Potential).
NP_BIND 102 109 ATP (Potential).
Comments:
-!- FUNCTION: May play a role in the repair of endogenous alkylation
damage.
-!- INTERACTION:
P13519:mreB; NbExp=1; IntAct=EBI-554597, EBI-371008;
-!- SIMILARITY: Belongs to the recA family. RadA subfamily.
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Sequence length: 460
MAKAPKRAFV CNECGADYPR WQGQCSACHA WNTITEVRLA ASPMVARNER LSGYAGSAGV
AKVQKLSDIS LEELPRFSTG FKEFDRVLGG GVVPGSAILI GGNPGAGKST LLLQTLCKLA
QQMKTLYVTG EESLQQVAMR AHRLGLPTDN LNMLSETSIE QICLIAEEEQ PKLMVIDSIQ
VMHMADVQSS PGSVAQVRET AAYLTRFAKT RGVAIVMVGH VTKDGSLAGP KVLEHCIDCS
VLLDGDADSR FRTLRSHKNR FGAVNELGVF AMTEQGLREV SNPSAIFLSR GDEVTSGSSV
MVVWEGTRPL LVEIQALVDH SMMANPRRVA VGLEQNRLAI LLAVLHRHGG LQMADQDVFV
NVVGGVKVTE TSADLALLLA MVSSLRDRPL PQDLVVFGEV GLAGEIRPVP SGQERISEAA
KHGFRRAIVP AANVPKKAPE GMQIFGVKKL SDALSVFDDL