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Description:
DNA repair protein recN (Recombination protein N).
Molecular weight: 61396
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
01-OCT-1996, sequence version 2.
07-MAR-2006, entry version 50.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Escherichia.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein RECN_ECOLI:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | Y00357 | CAA68435.1 | - |
| EMBL | U36840 | AAA79786.1 | - |
| EMBL | U00096 | AAT48145.1 | - |
| EMBL | D90888 | BAA16501.1 | - |
| PIR | C65040 | RQECN. | |
| GenomeReviews | U00096_GR | b2616.1 | |
| EchoBASE | EB0824 | -.1 | |
| EcoGene | EG10831 | recN. | |
| BioCyc | EcoCyc:EG10831-MONOMER | -.1 | |
| GO | GO:0005515 | F:protein binding | IPI. |
| InterPro | IPR003439 | ABC_transp_like. | |
| InterPro | IPR004604 | RecN. | |
| InterPro | IPR003395 | SMC_N. | |
| PANTHER | PTHR11059 | RecN.1 | 1. |
| Pfam | PF02463 | SMC_N | 1. |
| TIGRFAMs | TIGR00634 | recN | 1. |
Keywords:
ATP-binding; Complete proteome; DNA damage; DNA repair; Nucleotide-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX MEDLINE=87259985; PubMed=3037486;
RA Rostas K., Morton S.J., Picksley S.M., Lloyd R.G.;
RT "Nucleotide sequence and LexA regulation of the Escherichia coli recN
RT gene.";
RL Nucleic Acids Res. 15:5041-5049(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655;
RX MEDLINE=97426617; PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J.,
RA Mau B., Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1474(1997).
RN [3]
RP SEQUENCE REVISION TO 426.
RA Arnaud M., Berlyn M.K.B., Blattner F.R., Galperin M.Y., Glasner J.D.,
RA Horiuchi T., Kosuge T., Mori H., Perna N.T., Plunkett G. III,
RA Riley M., Rudd K.E., Serres M.H., Thomas G.H., Wanner B.L.;
RT "Workshop on annotation of Escherichia coli K-12.";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX MEDLINE=97349980; PubMed=9205837; DOI=10.1093/dnares/4.2.91;
RA Yamamoto Y., Aiba H., Baba T., Hayashi K., Inada T., Isono K.,
RA Itoh T., Kimura S., Kitagawa M., Makino K., Miki T., Mitsuhashi N.,
RA Mizobuchi K., Mori H., Nakade S., Nakamura Y., Nashimoto H.,
RA Oshima T., Oyama S., Saito N., Sampei G., Satoh Y., Sivasundaram S.,
RA Tagami H., Takahashi H., Takeda J., Takemoto K., Uehara K., Wada C.,
RA Yamagata S., Horiuchi T.;
RT "Construction of a contiguous 874-kb sequence of the Escherichia coli-
RT K12 genome corresponding to 50.0-68.8 min on the linkage map and
RT analysis of its sequence features.";
RL DNA Res. 4:91-113(1997).
Feature:
CHAIN 1 553 DNA repair protein recN.
/FTId=PRO_0000188017.
NP_BIND 29 36 ATP (Potential).
CONFLICT 59 60 AA -> C (in Ref. 1).
CONFLICT 76 76 A -> R (in Ref. 1).
CONFLICT 535 553 GGSEVTRNTLANAKELLAA -> VAVKSHVIHWRMRKNCLQ
RKLFSCFTVRVNSKTP (in Ref. 1).
Comments:
-!- FUNCTION: May be involved in recombinational repair of damaged
DNA.
-!- INTERACTION:
P36996:cspC; NbExp=1; IntAct=EBI-548098, EBI-547832;
P76104:ydcP; NbExp=1; IntAct=EBI-548098, EBI-556974;
-!- SIMILARITY: Belongs to the recN family.
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Sequence length: 553
MLAQLTISNF AIVRELEIDF HSGMTVITGE TGAGKSIAID ALGLCLGGRA EADMVRTGAA
RADLCARFSL KDTPAALRWL EENQLEDGHE CLLRRVISSD GRSRGFINGT AVPLSQLREL
GQLLIQIHGQ HAHQLLTKPE HQKFLLDGYA NETSLLQEMT ARYQLWHQSC RDLAHHQQLS
QERAARAELL QYQLKELNEF NPQPGEFEQI DEEYKRLANS GQLLTTSQNA LALMADGEDA
NLQSQLYTAK QLVSELIGMD SKLSGVLDML EEATIQIAEA SDELRHYCDR LDLDPNRLFE
LEQRISKQIS LARKHHVSPE ALPQYYQSLL EEQQQLDDQA DSQETLALAV TKHHQQALEI
ARALHQQRQQ YAEELAQLIT DSMHALSMPH GQFTIDVKFD EHHLGADGAD RIEFRVTTNP
GQPMQPIAKV ASGGELSRIA LAIQVITARK METPALIFDE VDVGISGPTA AVVGKLLRQL
GESTQVMCVT HLPQVAGCGH QHYFVSKETD GAMTETHMQS LNKKARLQEL ARLLGGSEVT
RNTLANAKEL LAA