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Description:
Protein uvp1.
Molecular weight: 22127
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
01-NOV-1990, sequence version 1.
07-FEB-2006, entry version 43.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Escherichia.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein UVP1_ECOLI:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | X16119 | CAA34249.1 | - |
| PIR | S04903 | S04903. | |
| HSSP | P03012 | 2RSL | |
| InterPro | IPR012287 | Homeodomain-rel. | |
| InterPro | IPR006120 | HTH_7. | |
| InterPro | IPR002197 | HTH_Fis. | |
| InterPro | IPR006118 | Recombinase_S. | |
| InterPro | IPR006119 | resolvase_N. | |
| Pfam | PF02796 | HTH_7 | 1. |
| Pfam | PF00239 | Resolvase | 1. |
| PRINTS | PR01590 | HTHFIS. | |
| PROSITE | PS00397 | RECOMBINASES_1 | FALSE_NEG. |
| PROSITE | PS00398 | RECOMBINASES_2 | 1. |
Keywords:
DNA damage; DNA integration; DNA invertase; DNA recombination; DNA repair; DNA-binding; Plasmid.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX MEDLINE=89384434; PubMed=2550763; DOI=10.1007/BF00330560;
RA Gigliani F., Sporeno E., Perri S., Battaglia P.A.;
RT "The uvp1 gene of plasmid pR cooperates with mucAB genes in the DNA
RT repair process.";
RL Mol. Gen. Genet. 218:18-24(1989).
Feature:
CHAIN 1 198 Protein uvp1.
/FTId=PRO_0000196385.
DNA_BIND 168 187 H-T-H motif (By similarity).
ACT_SITE 9 9 O-(5'-phospho-DNA)-serine intermediate
(By similarity).
Comments:
-!- FUNCTION: Cooperates with the mucAB genes in the DNA repair
process. Could be a resolvase-invertase protein.
-!- SIMILARITY: Belongs to the site-specific recombinase resolvase
family.
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Sequence length: 198
MIIGYARKST HLQDVTHQVD ELTKAGCEQI YHEQISRGGS KRAKNGAPEL ENCLKALREG
DTLVVWALDR LGGSLSQVIT LLDDLKKRGI TFIAIKDRID TSAPVIGEIY THLMAIFSNF
ERNRNIERTR SGLAAARARG RVGGRKPSLS EDDINEMKIL LADPEMTVGA VAKRFNVSRM
TIYRYTTKGN HSEKINDE