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Description:
Single-stranded DNA-binding protein 2 (SSB 2) (Helix-destabilizingprotein 2).
Molecular weight: 19381
View which proteins in this organism that is involved with DNA Repair;
classified after biological processes (using data from the GOA project):
DNA repair( GO:0006281 )
Important dates:
24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
01-MAY-2000, sequence version 1.
07-MAR-2006, entry version 32.
Phylogenetic order:
Bacteria Proteobacteria Gammaproteobacteria Enterobacteriales Enterobacteriaceae Salmonella.
To calculate the pI (Isoelectric point - the pH where a protein has a neutral charge),
go to this page and enter the protein ID (e.g 3MG_ECOLI): http://us.expasy.org/tools/pi_tool.html
Links to references in other databases for protein SSB2_SALTI:
| Database | Pointer | Add. info#1 | Add. info#2 |
| EMBL | AF000001 | AAF14810.1 | - |
| EMBL | AL627282 | CAD09315.1 | - |
| EMBL | AE014613 | AAO71699.1 | - |
| HSSP | P02339 | 1KAW | |
| SMR | Q9RHF4 | 2-121.1 | |
| GenomeReviews | AL513382_GR | STY4536.1 | |
| GenomeReviews | AE014613_GR | t4237.1 | |
| BioCyc | SENT209261:T4237-MONOMER | -.1 | |
| BioCyc | SENT90370:STY4536-MONOMER | -.1 | |
| InterPro | IPR012340 | OB_NA_bd_sub. | |
| InterPro | IPR011344 | Single_strand_bd. | |
| InterPro | IPR000424 | SSB_primosomal_n. | |
| InterPro | IPR010913 | ssDNA_bd. | |
| Pfam | PF00436 | SSB | 1. |
| TIGRFAMs | TIGR00621 | ssb | 1. |
| PROSITE | PS50935 | SSB | 1. |
Keywords:
Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding.
References:
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Ty2 / ATCC 700931;
RX MEDLINE=20278079; PubMed=10816445;
RX DOI=10.1128/IAI.68.6.3067-3073.2000;
RA Zhang X.-L., Tsui I.S.M., Yip C.M.C., Fung A.W.Y., Wong D.K.-H.,
RA Dai X.-Y., Yang Y., Hackett J., Morris C.;
RT "Salmonella enterica serovar typhi uses type IVB pili to enter human
RT intestinal epithelial cells.";
RL Infect. Immun. 68:3067-3073(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX MEDLINE=21534947; PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P.,
RA Cronin A., Davis P., Davies R.M., Dowd L., White N., Farrar J.,
RA Feltwell T., Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K.,
RA Krogh A., Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C.,
RA Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K.,
RA Whitehead S., Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella
RT enterica serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ty2 / ATCC 700931;
RX MEDLINE=22531367; PubMed=12644504;
RX DOI=10.1128/JB.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J.,
RA Burland V., Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2
RT and CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
Feature:
CHAIN 1 178 Single-stranded DNA-binding protein 2.
/FTId=PRO_0000096091.
DOMAIN 6 111 SSB.
Comments:
-!- FUNCTION: This protein is essential for replication of the
chromosome. It is also involved in DNA recombination and repair
(By similarity).
-!- SIMILARITY: Contains 1 SSB domain.
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Sequence length: 178
MASKGVNKVI LVGNLGQDPE VRYMPNGGAV VNLSLATSDT WTDKQTGDKK ERTEWHRVVL
YGKLAEIASE YLRKGSQVYI EGALRTRKWT DQSGVEKYTT EVVVSQSGTM QMLGGRNSAG
SGQQQGGWGQ PQQPAAPSHS GMPPQQHPAN EPPMDFDDDI PFAPFGHSVA RHALYVLS